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Manuscript calls for collaborative approach to drug development
"We hope our recommendations will reposition comparative oncology canine trials as integral and parallel to human development" - Dr Chand Khanna.
Manuscript will further new initiatives to expand awareness of comparative oncology.

A new WSAVA-supported manuscript has highlighted the value of collaboration between the human and animal pharmaceutical and biotech sectors in drug development.

The manuscript follows a workshop on comparative oncology, hosted by the WSAVA's One Health Committee (WSAVA OHC) at its 2019 World Congress in Toronto. The workshop was led by researchers in human and animal medicine and was attended by academics and industry representatives working in cancer research.

Many cancers that afflict dogs also occur in humans, giving researchers the chance to improve lives by studying cancers and treatments in parallel. Delegates at the workshop included other members of the WSAVA OHC, academics and industry representatives working in cancer research.

In the manuscript, researchers outline new commercial perspectives on the value of closer relationships between the human and animal health pharmaceutical and biotech sectors, to deliver a ‘win/win’ for successful cancer drug development in humans and dogs.

Manuscript author Dr Chand Khanna, from the American College of Veterinary Internal Medicine (Oncology), commented: “We hope our recommendations will reposition comparative oncology canine trials as integral and parallel to human development and that this move will create opportunities for step-wise iteration and the improvements in the human cancer drug development path that are increasingly necessary.”

Dr Michael Lappin, chair of WSAVA One Health Committee, added: “The field of comparative oncology as part of cancer drug development stands out as a successful example of the One Health approach to medicine and this new manuscript presents a nuanced and novel strategy to deliver this translational opportunity.”

The authors and the WSAVA OHC plan to use the manuscript as a springboard for further new initiatives to expand awareness of comparative oncology. They also hope to drive forward its use to create a closer alignment of human and animal health pharma and biotech.

The manuscript, entitled ‘Delivering innovation to oncology drug development through cancer drug DISCO (Development Incentive Strategy using comparative oncology): Perspectives, gaps and solutions’, is published in the journal Annals of Medicine and Clinical Oncology. 

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Practices urged to audit neutering data

News Story 1
 RCVS Knowledge has called on vet practices to audit their post-operative neutering outcomes.

It follows the release of the 2024 NASAN benchmarking report, which collates data from neutering procedures performed on dogs, cats and rabbits.

The benchmarking report enables practices in the UK and Ireland to compare their post-operative outcomes to the national average. This includes the rate of patients lost to follow-up, which in 2024 increased to 23 per cent.

Anyone from the practice can submit the data using a free template. The deadline for next report is February 2026.

Visit the RCVS Knowledge website to complete an audit. 

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News Shorts
RCVS pays tribute to well-loved equine vet

The RCVS and the Riding Establishments Subcommittee has paid tribute to well-loved veterinary surgeon and riding establishment inspector, Rebecca Hamilton-Fletcher MRCVS.

Linda Belton MRCVS, RCVS President, said: "I, along with my colleagues on the RESC, RCVS Council, RCVS Standards Committee, as well as RCVS staff, was very saddened to hear of the sudden death of Rebecca, or Becca as we knew her, last week.

"She was a true advocate for equine welfare and in her many years on the RESC worked to continually improve the quality and consistency of riding establishment inspections, all in the interests of enhanced horse welfare and rider safety."