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Discovery offers hope for anti-cancer therapy
Immunoglobulin E (IgE) antibodies are created when the immune system overreacts to an allergen.

Immunoglobulin E antibodies could fight cancer in humans and dogs

Antibodies that are produced in response to allergens could offer hope for a new anti-cancer therapy in dogs and humans, scientists have said.

Immunoglobulin E (IgE) antibodies are created when the immune system overreacts to an allergen, such as pollen. However, their original purpose is to repel harmful external substances.  

A team of international scientists have now developed a ‘canine IgE’ that targets the EGFR growth factor in cancerous tumours. In-vitro studies found that, in more than 60 per cent of cases, the tumour was destroyed by IgE antibodies.

IgE antibodies build a ‘bridge’ between EGFR on cancer cells and inflammatory cells, which releases tumour necrosis factors.

The study, published in the Journal of Allergy and Clinical Immunology, offers hope for humans too, as canine and human EGFR are a 92 per cent match.

Lead author Erika Jensen-Jarolim said: "We can therefore hope that we have made an important contribution towards developing a new form of immunotherapy against cancerous tumours.

"A subsequent clinical trial will be conducted in canine patients to validate the results in an international joint initiative before moving to human trials.”

Image © M. Bernkopf/Vetmeduni Vienna

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ISFM announces first veterinary nurse conference

News Story 1
 The International Society of Feline Medicine (ISFM) - the veterinary division of International Cat Care - has announced its first annual conference dedicated to veterinary nurses. The day offers an opportunity to meet up with colleagues and enjoy more than five hours of stimulating CPD.

The conference is being held at the Crowne Plaza Hotel, Stratford-Upon-Avon, on Saturday 15 September 2018. Tickets are £95 per person and include lunch, coffee breaks, downloadable proceedings and CPD certificate. For details and to book your place visit www.eventbrite.co.uk  

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WSAVA awards Australian vet with 'Next Generation’ award

Australian vet Dr Guyan Weerasinghe has been crowned winner of the WSAVA ‘Next Generation’ Veterinary Award. The award recognises those who graduated within the last 10 years and have made a significant contribution to the welfare of companion animals and the veterinary profession as a whole.

Besides maintaining a small animal caseload, Dr Weerasinghe works for the Queensland Government’s Department of Agriculture where he is involved with animal disease surveillance and increasing the public health risks in veterinary practice. He also collaborates on various One Health projects across Australia and gives regular talks on the impact of climate change on animal health and welfare.

Dr Weerasinghe will receive his award at the WSAVA World Congress 2018 (25-28 September).