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Discovery offers hope for anti-cancer therapy
Immunoglobulin E (IgE) antibodies are created when the immune system overreacts to an allergen.

Immunoglobulin E antibodies could fight cancer in humans and dogs

Antibodies that are produced in response to allergens could offer hope for a new anti-cancer therapy in dogs and humans, scientists have said.

Immunoglobulin E (IgE) antibodies are created when the immune system overreacts to an allergen, such as pollen. However, their original purpose is to repel harmful external substances.  

A team of international scientists have now developed a ‘canine IgE’ that targets the EGFR growth factor in cancerous tumours. In-vitro studies found that, in more than 60 per cent of cases, the tumour was destroyed by IgE antibodies.

IgE antibodies build a ‘bridge’ between EGFR on cancer cells and inflammatory cells, which releases tumour necrosis factors.

The study, published in the Journal of Allergy and Clinical Immunology, offers hope for humans too, as canine and human EGFR are a 92 per cent match.

Lead author Erika Jensen-Jarolim said: "We can therefore hope that we have made an important contribution towards developing a new form of immunotherapy against cancerous tumours.

"A subsequent clinical trial will be conducted in canine patients to validate the results in an international joint initiative before moving to human trials.”

Image © M. Bernkopf/Vetmeduni Vienna

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Fashion house Prada to stop using fur from 2020

News Story 1
 Italian fashion house Prada has become the latest clothing retailer to announce that it will no longer be using animal fur in its products.

In a press release, the Group said the new policy will commence from the Group’s Spring/Summer 2020 collection. The current inventory will be sold until quantities are exhausted.

Prada said the move comes following ‘positive dialogue’ with the Fur Free Alliance, the Humane Society of the United States and LAV, a European animal rights organisation. 

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BVA Scottish Branch welcomes new president

Moray vet Kathleen Robertson has been named president of the BVA’s Scottish Branch. She took over the role from Melissa Donald at the association’s annual general meeting on Tuesday (21 May).

A University of Glasgow graduate, Kathleen has held diverse positions spanning clinical practice, teaching, inspection and consultancy work. She sits on the Scottish Antimicrobial Stewardship Group, the Livestock Health Scotland Board and the Veterinary Delivery Landscape project. She is also an Honorary Secretary of the Society of Practising Veterinary Surgeons.