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Bacteria develop resistance from rivals - study
The overuse of antibiotics may not be exclusively responsible for antibiotic resistance.

Research works to tackle antibiotic resistance

The overuse of antibiotics may not be exclusively responsible for antibiotic resistance, according to new research.

The study by the University of Basel found that bacteria can develop resistance to antibiotics from their competitors.
Writing in Cell Reports, researchers show that some bacteria inject a toxic cocktail into their rivals leading to cell lysis and death.

Researchers also found that if the released material contains certain drug-resistant genes, the specific resistance can be bestowed upon the new owner. As such, the antibiotic is no longer effective and the bacteria can reproduce.

“Some of these toxic proteins kill the bacterial competition very effectively, but do not destroy the cells,” explained Professor Marek Basler, who led the research. “Others severely damage the cell envelope, which leads to less of the attacked bacteria and hence the release of its genetic material.”

In the study, the researchers analysed the drug-resistant bacterium Acinetobacter baumanni - a typical hospital germ that originated during the Iraq war. The bacteria is also known as the ‘Iraq bug’ because it was spread by American soldiers returning home from combat.

The team found that the emergence and spread of multidrug resistance could be attributed - amongst other things - to the skills of certain bacteria. First, the bacteria combat their rivals by injecting them with toxic proteins - or effectors - using the type VI secretion system (T6SS), a poison syringe. Second, they are able to uptake and reuse the released genetic material.

In the model Acinetobacter baylyi, a close relative of the Iraq bug, Professor Basler’s team identified five differently acting toxic effectors.

“For the bacteria it makes absolute sense to produce not only a single toxin, but a cocktail of various toxins with different effects,” Basler explains. “This increases the likelihood that the rival can be successful and in some cases also lysed to release their DNA.”

Professor Basler added that the T6SS 'can also be found in other pathogens such as those which cause pneumonia or cholera'.

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Wildlife presenter to deliver keynote speech at BVA Congress

News Story 1
 The BVA has confirmed wildlife presenter Mike Dilger will deliver the keynote speech at this yearís congress. Mike is known as ĎBritainís most diseased maní, having contracted a number of exotic diseases on his travels, including malaria, bilharzia and leishmaniasis. His talk, ĎMy diseases and other animalsí, promises to be an amusing and inspiring lecture on his travels in the tropics and his thoughts on how the mass media is influencing human engagement with wildlife and nature. The lecture will take place at 1pm on 16 November, in the BVA Congress Theatre at Londonís ExCeL. 

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Vet school runs event for aspiring vets and nurses

Bristol Veterinary School is hosting an event for aspiring vets and vet nurses, to allow them to experience life as a student and find out what itís like to work in veterinary medicine. The one-day event, called VetQuest, will be held at the Langford Campus and includes a tour, talks on admissions and work experience, and the chance to take part in practical sessions. Taking place on Saturday 27 October, the event is primarily aimed at 11-12 year olds and costs £50, including lunch. There are a limited number of subsidised tickets for £10. To book, visit VetQuest 2018