Cookie use on MRCVSonline
We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive all cookies.
If you would like to forward this story on to a friend, simply fill in the form below and click send.

Your friend's email:
Your email:
Your name:
Send Cancel

Atypical myopathy testing service launched
Atypical myopathy is caused by the ingestion of sycamore tree seeds or seedlings, which contain the toxin hypoglycin-A.

RVC hopes to improve understanding of the condition 

Testing for atypical myopathy is now being offered by the RVC as part of its work to develop improved treatments and management of the disorder.

Atypical myopathy is a life-threatening equine muscle disorder caused by the ingestion of sycamore tree seeds or seedlings, which contain the toxin hypoglycin-A.

The risk factors for horses are unclear. For example, it is not known whether some trees are more toxic than others, or whether the toxin levels vary at certain times of the year, or in certain climates.

Scientists have developed a more rapid test for hypoglycin-A and its principal metabolite MCPA-carnitine. The Comparative Neuromuscular Diseases Laboratory at the RVC is now offering testing for the toxin and its metabolite in serum from horses suspected of having atypical myopathy, or at-risk field companions.

The RVC’s lab also offers urine organic acid and plasma acyl carnitine profile testing, which support the diagnosis in this acquired form of multiple acyl-coA dehydrogenase deficiency. Samples must be submitted by vets.

Samples of sycamore seeds, seedlings and leaves are also being tested for horse owners who have concerns about trees on their properties. Owners can organise this directly with the lab.

Professor Richard Piercy, professor of comparative neuromuscular disease, commented: “Through working with vets and owners in this way and with the support of the Horse Trust and [RVC’s Animal Care Trust], we hope to be able to improve the understanding of the condition and improve the welfare of horses.”

Image courtesy of RVC


Become a member or log in to add this story to your CPD history

Mission Rabies 2017 off to a great start

News Story 1
 More than 4,500 dogs have been vaccinated against rabies in one of the first major drives of 2017.

It took just two weeks in January for Mission Rabies to vaccinate 4,575 dogs in the Meru district of Tanzania.

The team set-up vaccination points across the district and followed-up with door-to-door work, checking vaccination cards and giving vaccines to any dogs that had been missed.

Overall, the charity reached 75 per cent of the local dog population, smashing last year's total and comfortably above the required 70 per cent.  

News Shorts
US science association honours leading Pirbright scientist

A leading scientist at The Pirbright Institute has been honoured by the American Association for the Advancement of Science as a 2017-2018 AAAS Alan I. Leshner Leadership Institute Public Engagement Fellow.

Dr Anthony Wilson, group leader for integrative entomology at Pirbright, was chosen from a large number of international applicants, together with 14 other infectious disease researchers from around the world.

In selecting the new Public Engagement Fellows, the AAAS said they had demonstrated, "...leadership and excellence in their research careers and interest in promoting meaningful dialogue between science and society".