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Humans pass more viruses to animals, study finds
Researchers analysed nearly 12 million viral genomes.
Twice as many infections involved human-animal transmission than animal-human.

A study has revealed that more viral infections are anthroponotic, meaning that they are transferred from humans to domestic and wild animals, than are zoonotic.

An analysis of viral genome sequences demonstrated that roughly twice as many infections involved human-animal transmission than animal-human.

With many epidemic and pandemics, such as Ebola and Covid-19, resulting from zoonotic transmission, these diseases have often taken precedence as a threat to public health. This has led to humans being considered a sink for viruses, rather than a source.

To compare the amount of zoonotic and anthroponotic diseases, researchers from University College London (UCL) developed methodological tools that would enable them to analyse nearly 12 million viral genomes that were deposited on public databases.

This meant that they could reconstruct evolutionary histories and past host jumps of viruses across 32 viral families, considering which genomes developed mutations during host jumps. This would allow them to quantify where viruses occurred from animal-human, human-animal or animal-animal transmission.

The results highlighted a prevalence of human-animal transmissions, consistent across most viral families. It also discovered even more animal-animal transmissions, not involving humans.

Findings showed that viral host jumps were often related to an increase in genetic changes, or mutations, in the viruses, relative to their continued evolution alongside a host animal.

Viruses with broader host ranges showed weaker signs of adaptation, which suggested that they were inherently more capable of infecting a range of hosts. Other viruses may require more extensive adaptation to infect a new host species.

Prof Francois Balloux, a co-author of the study from the UCL Genetics Institute, said: "We should consider humans just as one node in a vast network of hosts endlessly exchanging pathogens, rather than a sink for zoonotic bugs.

"By surveying and monitoring transmission of viruses between animals and humans, in either direction, we can better understand viral evolution and hopefully be more prepared for future outbreaks and epidemics of novel illnesses, while also aiding conservation efforts.”

The full study can be found in the journal Nature Ecology & Evolution.

Image © Shutterstock

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Prof Joanne Webster elected as Fellow of the Royal Society

News Story 1
 Joanne Webster, a professor of parasitic diseases at the RVC, has been elected as a Fellow of the Royal Society (FRS).

An infectious disease expert, Prof Webster is known for promoting a One Health approach to disease control.

She completed her doctoral research in zoonotic disease and parasite-host interactions, and has since earned widespread recognition for contributions to parasitology and global health.

Prof Webster said: "I am truly honoured, and somewhat stunned, to be recognised alongside such an exceptional group of scientists." 

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Germany FMD import restrictions eased

The UK government has lifted the import restrictions placed on FMD-susceptible commodities from Germany.

The decision comes after the country was recognised as foot-and-mouth disease free without vaccination on 14 May.

Imports of FMD-susceptible animals and their by-products from Germany were originally banned, after the country reported a case of FMD near Brandenburg in January. In March, the UK government permitted imports from outside of the outbreak zone.

Germany will now be able to import FMD-susceptible animals and their by-products into the UK, providing they meet other import conditions.

The decision follows rigorous technical assessment of measures in Germany. Defra says it will not hesitate respond to FMD outbreaks.