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New genetic test for DEPOH in sighthounds
DEPOH is an important health problem in certain sighthound breeds.

The test will allow vets to target the use of preventative medication.

Researchers at Washington State University, supported by the Scottish Deerhound Club of America, have developed a new genetic test that can identify dogs at risk of a condition known as delayed postoperative haemorrhage (DEPOH). The disorder can result in excessive bleeding and bruising in the hours and days after major surgery.

The test was developed following a study of 269 privately owned deerhounds. The dogs were evaluated with an objective of identifying genes associated with DEPOH.

The researchers used genome-wide association analysis to identify a single region on chromosome 9 that contained 40 candidate genes. Further screening of the candidate genes was performed and only the DEPOH gene was identified as being directly linked to the pathophysiology of the disorder.

DEPOH is a potentially fatal disorder that can vary in severity from minor bruising to life-threatening haemorrhaging. The condition typically occurs one to four days after major surgery when blood clots begin to break down too soon, in a process called hyperfibrinolysis.

First identified in racing greyhounds in 2007, DEPOH is an important health problem in certain sighthound breeds, including Scottish deerhounds and greyhounds. Following the identification of the DEPOH gene, the mutation has been discovered in additional sighthounds such as Italian greyhounds and salukis, as well as other breeds including golden retrievers and border collies.

Dogs with a mutation of the DEPOH gene are at higher risk than other dogs of developing the condition post surgery. The new test will allow veterinary surgeons to administer antifibrinolytic drugs to those that test positive for the gene before any surgery.

Previously, veterinary surgeons would have had to administer preventative medication indiscriminately, which can be costly and lead to adverse reactions.

Health and genetics commission chair for the Scottish Deerhound Club of America Dr. John Dillberger said: “Now pet owners can test their dog at any time in its life to understand whether it is at risk.

“And if it is, before planning any scheduled or elective surgery, they can make sure the surgeon is aware of it and prepare accordingly. This will help save the lives of pets.”

The study has been published by the Journal of Veterinary Medicine.

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Survey launched to investigate EHV

News Story 1
 Zoetis has launched a new survey to identify management techniques for Equine Herpes Virus (EHV).

EHV is a contagious, airborne virus that can cause respiratory problems and severe diseases in horses and ponies. It spreads among horses over short distances, direct contact and through shared equipment.

The survey will explore current knowledge and management practices with EHV in the UK. It is quick to complete and participants could win one of 10 equine first aid kits.

Complete the survey here

Click here for more...
News Shorts
WSAVA launches pet travel guidance factsheet

A new pet travel guidance factsheet for veterinary professionals and caregivers has been developed by the WSAVA in collaboration with the World Veterinary Association.

The Dog and Cat Welfare During Transport factsheet provides step-by-step guidance for all stages of a journey, from pre-travel checklists to post-travel care.

Brachycephalic breeds or animals prone to travel-related anxiety are given special focus in this guide, which also provides links to IATA container regulation and WSAVA vaccination guidelines.