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RVC study offers hope for osteoporosis sufferers
An estimated 500,000 people are hospitalised every year for fractures owing to osteoporosis.
Researchers present NaQuinate treatment found to prevent bone loss.

Researchers at the Royal Veterinary College (RVC) have highlighted a promising new treatment for people living with skeletal disorders.

Scientists say the treatment - NaQuinate - presented today (11 September) at the American Society of Bone and Mineral Research (ASBMR), could be used to manage osteoporosis, a debilitating condition that affects more than three million people in the UK.

NaQuinate is a naturally occurring metabolite of vitamin K. Previous studies have shown that it can protect against the loss in bone quality that occurs in ovariectomy in mouse and rat models.

In this new study, NaQuinate was also shown to significantly synergise with mechanical loading in targeted regions of cortical bone. The treatment is currently in Phase I clinical trials to establish its safety and efficacy as a treatment for post-menopausal women with osteoporosis.

Professor Andrew Pitsillides, Professor of Skeletal Dynamics at the RVC, said: “There are three main ways to maintain bone quality and strength to resist fracture: stop bone loss, build mass and enhance the topographical changes to optimise and enhance weight-bearing roles. It may be that NaQuinate can achieve a balance of all three to treat osteoporosis and better maintain healthy ageing.”

An estimated 500,000 people are hospitalised every year for broken bones owing to osteoporosis. The condition causes a significant social and economic burden, with breaks often leading to a downward spiral of disability, loss of independence and increased mortality.

Prof Pitsillides added: “At the RVC we recognise the importance of a collaborative ‘One Health’ approach which operates at the cutting edge of veterinary and human medicine, and this research could pave the way for a novel treatment for this common and debilitating condition.”

The study was developed in collaboration between the Skeletal Biology group at the RVC and biotechnology company Haoma Medica.

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Government to run free webinars on exporting horses

News Story 1
 The UK government has announced that it will be running two free webinars for horse owners and exporters, explaining what steps to take to export horses from 1 January 2021.

The first webinar will take place on Tuesday 20 October 2020, from 9.30am to 11am. It will cover Export Health Certificate (EHC) requirements from 1 January 2021. Click here to register.

The second webinar will take place on Wednesday 4 November 2020, from 10.30am to 12pm. This session will focus on the steps that businesses need to take to export equines from the UK to the EU. Click here to register.

For more information on exporting horses and ponies after 1 January 2021, please visit the gov.uk website. 

Click here for more...
News Shorts
More cases of African swine fever confirmed in Germany

More cases of African swine fever (ASF) have been confirmed in wild boar in Germany.

According to Pig World, 20 outbreaks have been identified in two districts - Brandenburg, where the original case confirmed on September 10 was found, and near the town of Neuzelle, some 7.5 km away.

The finding represents a further seven cases confirmed by Germany's Friedrich-Loeffler Institute. A Central Crisis Team has been established to coordinate the response to the outbreak.