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RVC study reveals insights on tendon disease
“Our results show that proteins within tendon are renewed much more rapidly than previously thought" - Dr Chavaunne Thorpe.
Scientists examined protein turnover rates in the tendons of rats.

New treatments for tendon disease and other musculoskeletal disorders could be on the horizon thanks to research by the Royal Veterinary College (RVC).

In the study, scientists examined protein turnover rates in the tendons of rats and found that tendons are dynamic tissue with varying turnover rates of proteins.

It is hoped the discovery could eventually provide a greater understanding of how tendon disease and other connective tissue disorders can be treated.

Dr Chavaunne Thorpe, Versus Arthritis Career Development Fellow at the RVC and author of the paper, explains: “Our results show that proteins within tendon are renewed much more rapidly than previously thought, with different rates of turnover in different regions of the tendon.

“These findings will help us to understand how the rate of protein renewal in tendon is affected by ageing or injury and will allow future studies to identify potential targets for treatment of tendon disease and other prominent diseases which are caused by alterations in protein turnover rates.”

The study built on previous research that found that the interfascicular matrix - the main load-bearing structures of the tendon - allows sliding between fascicles, meaning that it may be prone to damage.

In this latest study, scientists sought to establish if the turnover rate of proteins in the interfascicular matrix is greater than in the fascicles, which would help repair any damage. The results are published in the journal Structural Biology and Molecular Biophysics.

'The discovery challenges long-held beliefs that almost no protein turnover occurs in tendon and instead, provides the first step in understanding how altered protein turnover contributes to the development of tendon disease,' the researchers note.

'Additionally, with alterations in protein turnover rates contributing to other musculoskeletal and connective tissue diseases, this study will also help target future research into how these diseases can most effectively be treated.'

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FIVP launches CMA remedies survey

News Story 1
 FIVP has shared a survey, inviting those working in independent practice to share their views on the CMA's proposed remedies.

The Impact Assessment will help inform the group's response to the CMA, as it prepares to submit further evidence to the Inquiry Group. FIVP will also be attending a hearing in November.

Data will be anonymised and used solely for FIVP's response to the CMA. The survey will close on Friday, 31 October 2025. 

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News Shorts
CMA to host webinar exploring provisional decisions

The Competition and Markets Authority (CMA) is to host a webinar for veterinary professionals to explain the details of its provisional decisions, released on 15 October 2025.

The webinar will take place on Wednesday, 29 October 2025 from 1.00pm to 2.00pm.

Officials will discuss the changes which those in practice may need to make if the provisional remedies go ahead. They will also share what happens next with the investigation.

The CMA will be answering questions from the main parties of the investigation, as well as other questions submitted ahead of the webinar.

Attendees can register here before Wednesday, 29 October at 11am. Questions must be submitted before 10am on 27 October.

A recording of the webinar will be accessible after the event.