Cookie use on MRCVSonline
We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive all cookies.
If you would like to forward this story on to a friend, simply fill in the form below and click send.

Your friend's email:
Your email:
Your name:
 
 
Send Cancel

Gene-edited chicken cells prevent spread of avian flu
The team stopped the virus from spreading by removing a section of chicken DNA inside laboratory-grown cells.

Findings increase likelihood of producing gene-edited chickens

Scientists at the University of Edinburgh have used gene editing techniques to prevent avian influenza virus spreading in laboratory-grown chicken cells.

Researchers say the findings increase the likelihood of producing gene-edited chickens that are resistant to the disease.

The team stopped the virus from spreading by removing a section of chicken DNA inside laboratory-grown cells. The next step will be to produce chickens with the genetic change.

“This is an important advance that suggests we may be able to use gene-editing techniques to produce chickens that are resistant to bird flu,” said Dr Mike McGrew, of the University of Edinburgh’s Roslin Institute. “We haven’t produced any birds yet and we need to check if the DNA change has any other effects on the bird cells before we can take this next step.”

In the study, scientists targeted a specific molecule inside chicken cells called ANP32A. Researchers at Imperial College London found that influenza viruses hijack this molecule during an infection to help replicate themselves.

Together with scientists at the University of Edinburgh’s Roslin Institute, the researchers then used gene-editing techniques to delete the section of DNA responsible for producing ANP32A. They found that the avian flu virus was not able to grow inside cells with the genetic change.

“Avian influenza resistance in broiler production is of global significance and this research is an important step toward that goal," commented Rachel Hawken of Cobb-Vantress, which provided the PhD student funding for the project.

"It is exciting for Cobb to be a part of exploring new technologies that could be used to advance poultry breeding in the future.”

 

Become a member or log in to add this story to your CPD history

Big Butterfly Count returns

News Story 1
 The world's biggest survey of butterflies is back for 2020!

Butterfly Conservation's Big Butterfly Count launches on Friday, 17 July and will run until Sunday 9 August. Members of the public can get involved by downloading the Big Butterfly Count App or recording results on a downloadable sheet available from bigbutterflycount.org/.

'It's a fantastic activity for people from three to 103 years and we'd encourage everyone to take 15 minutes in an appropriate outdoor space during sunny conditions to simply appreciate the nature around them and do their bit to help us understand butterfly populations,' said a Butterfly Conservation spokesperson. 

Click here for more...
News Shorts
New appointment at Dechra

Dechra Veterinary Products Ltd (Dechra) has announced a key appointment to support veterinary professionals across Northern Ireland and the Republic of Ireland.

Karen Hockley has been appointed as a telesales account manager and will provide the latest products, news and developments from Dechra. She joins the company from a large mixed practice in Northern Ireland where she was the branch manager.

Before that, Karen had worked for a multinational veterinary pharmaceutical company as a key account manager for Northern Ireland. She can be contacted at karen.hockley@dechra.com or 087 219 54 30.