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Stem cells ‘could be used as an alternative to antibiotics’
"...MSCs could prove useful against antimicrobial resistance and be used as an alternative to antibiotics.”

Study finds MSCs in horses fight bacterial infection 

Stem cells found in horses naturally produce molecules that can fight bacterial infection, according to new research by the Roslin Institute.

The team examined mesenchymal stem cells (MSCs), which are seen in animals and humans and can differentiate into a variety of cell types.

They discovered that MSCs may be able to fight infection in two ways - by acting directly on bacteria and by regulating the activity of immune cells involved in the body’s natural defences.

The endometrium was identified as a particularly promising novel source of MSCs for clinical applications in horses - and likely in other species too.

MSCs obtained from bone marrow or adipose tissue have been used for clinical tissue regeneration in animals for more than 10 years, which scientists say assures their safe use as potential clinical antimicrobials in the future.

Lead author Dr Cristina Esteves said: “This study shows that equine MSCs may act to defend the body against bacterial infection.

"We’re excited about these results as MSCs could prove useful against antimicrobial resistance and be used as an alternative to antibiotics.”

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Defra shares new Sanitary and Phytosanitary guidance

News Story 1
 Defra has published guidance for the vet sector ahead of a proposed UK-EU Sanitary and Phytosanitary agreement.

The agreement, which will change the movement and trade of animals and related products, could see reductions in checks, paperwork and certification. As well as describing regulatory developments, the advice highlights the importance of animal ID, registration and traceability in disease control and other compliance arrangements.

The guidance can be found here. More detail is expected as negotiations progress. 

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News Shorts
Lords Committee opens Pet Parasite Medication inquiry

The House of Lords Environment and Climate Change Committee will launch its inquiry into Pet Parasite Medication (PPM) on Wednesday (3 June).

Focusing on treatments containing fipronil and imidacloprid, the inquiry will seek to understand distribution pathways and the impacts of PPM use and non-use on biodiversity and human health. It will also cover current regulation, monitoring, and the potential implications for pets and their owners.

The committee will hear evidence from environmental non-governmental organisations and research institutes. The public can follow the proceedings live on Parliament TV or in person in the Palace of Westminster.