Your data on MRCVSonline
The nature of the services provided by Vision Media means that we might obtain certain information about you.
Please read our Data Protection and Privacy Policy for details.

In addition, (with your consent) some parts of our website may store a 'cookie' in your browser for the purposes of
functionality or performance monitoring.
Click here to manage your settings.
If you would like to forward this story on to a friend, simply fill in the form below and click send.

Your friend's email:
Your email:
Your name:
 
 
Send Cancel

New heart disease drug offers hope for cats and humans
HCM is one of the most commonly diagnosed diseases in cats.

MYK-461 proven effective in a study of five cats

A new drug for treating heart disease offers hope for both cats and humans, according to researchers at the University of California, Davis, School of Veterinary Medicine.

Writing in the journal PLOS One, the team describes how the new drug - MYK-461 - proved effective in a study of five cats.  

Each cat had a naturally inherited form of inherited hypertrophic cardiomyopathy (HCM), which is currently incurable and also affects humans.

“This is an exciting discovery for both animals and humans – an excellent representation of the One Health concept in action,” said Associate Professor Joshua Stern, chief of the Cardiology Service at the UC Davis veterinary hospital.

“The positive result in these five cats shows that MYK-461 is viable for use in cats as a possible option to halt or slow the progression of HCM.”

HCM is one of the most commonly diagnosed diseases in cats and causes the walls of the left ventricle to thicken. This decreases the effectiveness of the heart, making it harder to pump blood around the body.  

In humans, HCM affects 1 in 500 people in the UK. But most people with the disease show few, if any, symptoms.

In the study, researchers treated five cats suffering from HCM with MYK-461 and found that it eliminated obstruction in the left ventricle.
The drug is the first of its kind and is unique in the way it addresses the functional changes seen in human and feline HCM.

“There has been little to no progress in advancing the treatment of HCM in humans or animals for many years,” added Professor Stern. “This study brings new hope for cats and people.”

UC Davis now hopes to conduct a clinical trial of the drug to see if MYK-461 could become the accepted protocol for care of cats with HCM. 

Become a member or log in to add this story to your CPD history

Survey launched to investigate EHV

News Story 1
 Zoetis has launched a new survey to identify management techniques for Equine Herpes Virus (EHV).

EHV is a contagious, airborne virus that can cause respiratory problems and severe diseases in horses and ponies. It spreads among horses over short distances, direct contact and through shared equipment.

The survey will explore current knowledge and management practices with EHV in the UK. It is quick to complete and participants could win one of 10 equine first aid kits.

Complete the survey here

Click here for more...
News Shorts
WSAVA launches pet travel guidance factsheet

A new pet travel guidance factsheet for veterinary professionals and caregivers has been developed by the WSAVA in collaboration with the World Veterinary Association.

The Dog and Cat Welfare During Transport factsheet provides step-by-step guidance for all stages of a journey, from pre-travel checklists to post-travel care.

Brachycephalic breeds or animals prone to travel-related anxiety are given special focus in this guide, which also provides links to IATA container regulation and WSAVA vaccination guidelines.