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Wasps Create a Buzz with Antibiotics
Scientists have found that Digger wasps of the genus Philanthus, so-called beewolves, house beneficial bacteria on their cocoons that guarantee protection against harmful microorganisms.

Scientists of the Max Planck Institute for Chemical Ecology in Jena and researchers at the University of Regensburg and the Jena Leibniz Institute for Natural Product Research discovered that bacteria of the genus Streptomyces produce a cocktail of nine different antibiotics, thereby fending off invading pathogens.

Many insects spend a part of their life underground and are exposed to the risk of fungal or bacterial infections. This is also the case for many digger wasp species that construct underground nests. Unlike bees that use pollen and nectar as food to nurture their larvae, digger wasps hunt insects to feed their offspring. Because of the warm and humid conditions as well as the large amounts of organic material in their subterranean nest, both their food supply and their larvae are endangered by pathogens. Mold and bacterial infection are a major threat and can cause larval death in many cases.

Antibiotics on the surface of the cocoon, produced by symbionts, guarantee protection against microbial pests during such a protracted developmental stage.

An analysis of the substances involved not only contributes to the understanding of the evolution of such symbioses, but could also lead to the discovery of interesting new drug candidates for human medicine.
Using imaging techniques based on mass spectrometry, the antibiotics could be displayed in vivo on the cocoon’s exterior surface. Moreover, it was shown that the use of different kinds of antibiotics provides an effective protection against infection with a multitude of different pathogenic microorganisms. Thus, for millions of years beewolves have been taking advantage of a principle that is known as combination prophylaxis in human medicine.

With their work the researchers are breaking new ground: "Astonishingly, little is known about the ecological importance of antibiotics in their natural environment. Supported by mass spectrometric imaging we are now able to better understand the natural role of antibiotic substances in the environment," says Aleš Svatoš, leader of the mass spectrometry research group.

"We suppose that protective symbioses like the ones between beewolves and Streptomyces bacteria are much more common in the animal kingdom than previously assumed," says Martin Kaltenpoth. "An analysis of the substances involved not only contributes to the understanding of the evolution of such symbioses, but could also lead to the discovery of interesting new drug candidates for human medicine."

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Birmingham Dogs Home makes urgent appeal

News Story 1
 Birmingham Dogs Home has issued an urgent winter appeal as it faces more challenges over the Christmas period.

The rescue centre has seen a dramatic increase in dogs coming into its care, and is currently caring for over 200 dogs. With rising costs and dropping temperatures, the charity is calling for urgent support.

It costs the charity £6,000 per day to continue its work.

Fi Harrison, head of fundraising and communications, said: "It's heart-breaking for our team to see the conditions some dogs arrive in. We really are their last chance and hope of survival."

More information about the appeal can be found here. 

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Avian flu confirmed at premises in Cornwall

A case of highly pathogenic avian influenza H5N1 has been detected in commercial poultry at a premises near Rosudgeon, Cornwall.

All poultry on the infected site will be humanely culled, and a 3km protection zone and 10km surveillance zone have been put in place. Poultry and other captive birds in the 3km protection zone must be housed.

The case is the second avian flu case confirmed in commercial poultry this month. The H5N5 strain was detected in a premises near Hornsea, East Riding of Yorkshire, in early November. Before then, the disease had not been confirmed in captive birds in England since February.

The UK chief veterinary officer has urged bird keepers to remain alert and practise robust biosecurity.

A map of the disease control zones can be found here.