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Vaccine for Malignant Catarrhal Fever?
The annual wildebeest migration - one of the world's greatest spectacles but also a real threat to the livelihood of local farms.
The annual migration of over a million wildebeest across the Serengeti and Maasai Mara is often described as one of the greatest spectacles on earth. However, this natural wonder poses a real threat to the livelihood of local farmers whose cattle are essential to their economic and social welfare.

RESEARCHERS led by David Haig, Professor of Animal Infection and Immunity at The University of Nottingham have already developed a candidate MCF vaccine for use in cattle. The next step is to test it in field conditions. Over the next three years his research team will test the vaccine in Tanzania, develop it further as required and then look to make a new vaccine for a sheep virus which is very similar to the wildebeest virus and causes MCF in livestock in other parts of the world, including Europe, Indonesia, Australasia and the Americas.

Professor Haig, from the School of Veterinary Medicine and Science, said: “The quest for a vaccine for Malignant Catarrhal Fever goes back to the middle of the last century. We have the first successful vaccine candidate and this is eagerly sought by the pastoralists and farmers in Eastern and Southern Africa, who have been lobbying for this for many years. We also have a strategy to develop a vaccine for a related virus causing MCF elsewhere in the world and are delighted that BBSRC/DFID have given us the opportunity to develop this.”

The research project is part of a £13m initiative... to support farmers and families in the developing world.
The research project is part of a £13m initiative funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and the Department for International Development (DFID) to support farmers and families in the developing world.

Professor Haig will be working with experts from Glasgow University, the Moredun Research Institute, in Scotland, and Sokoine University of Agriculture in Tanzania, the Tanzania Wildlife Research Institute (TAWIRI), Tanzania National Parks (TANAPA), Central Veterinary Laboratory, and VETAID, Tanzania.

Agriculture is vital for the livelihoods of 75 per cent of the world's poor. Food demand is predicted to increase by 50 per cent by 2030. The BBSRC and DFID have joined forces to harness the UK's world-class bioscience base to address the challenges posed by livestock diseases and work with developing countries to provide practical and sustainable solutions.

‘Combating Infectious Diseases of Livestock for International Development’ is an initiative made up of 16 projects, involving 16 UK institutions and eight other countries, which over the next four years will look at some of the most prevalent, damaging and costly diseases of livestock in developing countries and work with more than 20 overseas institutes to not only control or prevent these diseases but also to build scientific capacity at a local and national level within these countries to enable them to manage these diseases and apply new findings and technologies to other disease areas, in both livestock and humans.

‘Combating Infectious Diseases of Livestock for International Development’ is an initiative made up of 16 projects, involving 16 UK institutions and eight other countries, which will look at some of the most prevalent, damaging and costly diseases of livestock in developing countries.
The projects will also offer significant benefits to farmers and consumers in the UK — animal diseases do not respect national boundaries and are estimated to have cost the UK economy over £15 billion over the past 15 years. Several of the diseases being tackled by the initiative are spreading across countries and continents and some are already a direct threat to UK livestock such as Foot and Mouth disease and Bluetongue virus. New technologies developed as part of this research could also be transferable for use to combat other animal diseases and possibly human ones too.

Science and Innovation Minister Lord Drayson said: “This collaboration demonstrates the UK's determination to share our world-leading science in the search for improved treatments and diagnostic tools in animal health. Animal disease is a deadly threat that leaves no corner of the Earth untouched. This research will allow communities to protect food chains and economies at home and in developing countries.”

By bringing together the best science and the brightest minds from around the globe, the initiative aims to generate workable solutions on the ground to improve animal welfare, productivity and ultimately enhance the lives of millions of people.

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Birmingham Dogs Home makes urgent appeal

News Story 1
 Birmingham Dogs Home has issued an urgent winter appeal as it faces more challenges over the Christmas period.

The rescue centre has seen a dramatic increase in dogs coming into its care, and is currently caring for over 200 dogs. With rising costs and dropping temperatures, the charity is calling for urgent support.

It costs the charity £6,000 per day to continue its work.

Fi Harrison, head of fundraising and communications, said: "It's heart-breaking for our team to see the conditions some dogs arrive in. We really are their last chance and hope of survival."

More information about the appeal can be found here

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Avian flu confirmed at premises in Cornwall

A case of highly pathogenic avian influenza H5N1 has been detected in commercial poultry at a premises near Rosudgeon, Cornwall.

All poultry on the infected site will be humanely culled, and a 3km protection zone and 10km surveillance zone have been put in place. Poultry and other captive birds in the 3km protection zone must be housed.

The case is the second avian flu case confirmed in commercial poultry this month. The H5N5 strain was detected in a premises near Hornsea, East Riding of Yorkshire, in early November. Before then, the disease had not been confirmed in captive birds in England since February.

The UK chief veterinary officer has urged bird keepers to remain alert and practise robust biosecurity.

A map of the disease control zones can be found here.