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Researchers seek cats with FIP for new study
Until recently, FIP was an invariably fatal disease, but new research offers hope.
The study aims to improve diagnosis, treatment and prognosis.

A research team at the University of Edinburgh Royal (Dick) School of Veterinary Studies is looking to recruit approximately 100 cats for a new study into feline infectious peritonitis (FIP). 

Cats with either wet or dry FIP can be enrolled in the study as long as they have had their diagnosis confirmed using the ABCD Algorithm and their owners have given written informed consent. Each cat will stay under the care of their GP veterinarian, with support from the study clinicians.

FIP is a viral disease in young cats, and occasionally older ones, caused by a coronavirus. Until recently, it was nearly always fatal, but research into COVID-19 has suggested that GS-441524 and its prodrug remdesivir can successfully be used to treat it. 

However, diagnosing the disease is still difficult. With an effective treatment now available, it is important to create a definitive test to diagnose and monitor the disease.

The researchers plan to evaluate two diagnostic possibilities: acute-phase proteins (APPs) and micro-RNA (mrRNA) in blood and effusions. It is hoped that at least one of these can be used to develop a reliable test for diagnosis, monitoring and prognosis of FIP.

Case histories and owner questionnaires will help the team to assess whether specific APPs and/or miRNA profiles can be used to predict how well a cat will respond to treatment. 

Prof Danièlle Gunn-Moore, part of the research team, said: “I undertook a PhD study into FIP in 1994 because I had seen so many beautiful kittens die from this hideous disease. I never imagined that I would now be able to treat so many of these precious babies so successfully. It really is the most important thing to happen in feline medicine in my lifetime. I am proud to be part of a group of people who are trying to work out the best way to use these drugs.”

More information about the study, including the participant information sheet and consent form, can be found here.

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Birmingham Dogs Home makes urgent appeal

News Story 1
 Birmingham Dogs Home has issued an urgent winter appeal as it faces more challenges over the Christmas period.

The rescue centre has seen a dramatic increase in dogs coming into its care, and is currently caring for over 200 dogs. With rising costs and dropping temperatures, the charity is calling for urgent support.

It costs the charity £6,000 per day to continue its work.

Fi Harrison, head of fundraising and communications, said: "It's heart-breaking for our team to see the conditions some dogs arrive in. We really are their last chance and hope of survival."

More information about the appeal can be found here. 

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Avian flu confirmed at premises in Cornwall

A case of highly pathogenic avian influenza H5N1 has been detected in commercial poultry at a premises near Rosudgeon, Cornwall.

All poultry on the infected site will be humanely culled, and a 3km protection zone and 10km surveillance zone have been put in place. Poultry and other captive birds in the 3km protection zone must be housed.

The case is the second avian flu case confirmed in commercial poultry this month. The H5N5 strain was detected in a premises near Hornsea, East Riding of Yorkshire, in early November. Before then, the disease had not been confirmed in captive birds in England since February.

The UK chief veterinary officer has urged bird keepers to remain alert and practise robust biosecurity.

A map of the disease control zones can be found here.