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Scientists make breakthrough in tackling toxic weeds
Understanding the link between certain weeds and the fungus would benefit the health of livestock across the world.

The project aims to combat the fatal effects of locoweeds to livestock.

Researchers in Wales have made significant progress in efforts to prevent weeds from poisoning livestock.

Working in collaboration with Northwest University, China, the team from Aberystwyth University has been examining why some weeds become toxic when a certain fungus grows inside them.

The fungus, Alternaria Oxytropis, lives inside locoweed plants, like Oxytropis and Astragalus, creating a poison that can be fatal to livestock. Through their investigations, the researchers have been instrumental in understanding how the fungus and plant interact, and can explain how the toxin develops in this fungus.

The mycotoxin harms the normal biochemical processes in animals like horses and sheep, leading to neurological illness and death. Farmers in nations like the United States and China are most affected by the issue, as governments and industry use pesticides to eradicate the hazardous weeds at a significant financial and environmental cost.

New Zealand faced a similar problem in ryegrass 20 years ago, which was solved through the successful selection of toxin-free endophyte strains.

Professor Luis Mur from Aberystwyth University said: “We are working to try to understand the symbiosis between these weeds and the fungus. By understanding the relationship, we can look to produce non-toxic strains. Not only would this be good for the health of livestock and for farmers around the world, it would also reduce herbicide use. There are major environmental as well as economic and animal health benefits from cracking the code.”

“Our research is focussing on trying to kick the fungus out of this plant. The success in New Zealand in producing strains of ryegrass that do not turn toxic is an example for us to follow.”

Dr Wei He from Northwest University in China added: “Understanding the relationship between the plant and the fungus is very important to Chinese agriculture. Thanks to the collaborative research with Aberystwyth University, we have helped understand the mechanisms through which plant and fungus interact. Importantly, we have helped to describe how the toxin is produced in this fungus.

“We are confident our ongoing collaboration will help deal with the detrimental effects of locoweeds to livestock.”

Image © Dr Wei He / Prof. Baoyu Zhao

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Equine Disease Surveillance report released for Q4 2025

News Story 1
 The latest Equine Disease Surveillance report has been released, with details on equine disease from Q4 of 2025.

The report, produced by Equine Infectious Disease Surveillance, includes advice on rule changes for equine influenza vaccination.

Statistics and maps detail recent outbreaks of equine herpes virus, equine influenza, equine strangles and equine grass sickness. A series of laboratory reports provides data on virology, bacteriology, parasitology and toxicosis.

This issue also features a case study of orthoflavivus-associated neurological disease in a horse in the UK. 

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News Shorts
BSAVA announces 12th Edition of the Small Animal Formulary

The BSAVA has published an updated edition of its Small Animal Formulary, which includes new drug monographs and emergency drug doses for rabbits, rodents, birds and reptiles.

One of BSAVA's most trusted and widely used clinical resources, this 12th edition of the manual also includes seven new client information leaflets and information on drugs used for the management of urinary incontinence.

Part A of the Formulary, Canine and Feline, sees Fergus Allerton return as Editor-in-Chief, while Part B: Exotic Pets was edited by Joanna Hedley. For more information, visit the BSAVA website.