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DNA test detects Lyme disease in horses
"The method is like having a special, specific 'fishhook' that only grabs Borrelia DNA and not the DNA of other microbes, nor the DNA of the host" - Prof Steven Schutzer.
The method works by isolating DNA from the microorganism causing the disease.  
 
A team of scientists from New Jersey have developed an advanced DNA test capable of identifying Lyme disease in a sick horse.

Professor Steven Schutzer, a professor of medicine at Rutgers University, and his team used their “genomic hybrid capture assay” to detect the disease agent – Borrelia burgdorferi – in a sample of the horse's spinal fluid. 

The test, described in the Journal of Veterinary Diagnostic Investigation, works by isolating DNA from the microorganism causing the disease. 

Schutzer explained: "The method is like having a special, specific 'fishhook' that only grabs Borrelia DNA and not the DNA of other microbes, nor the DNA of the host (animal or human). Detecting DNA of the disease is a direct test, meaning we know you have active disease if it's circulating in the blood or spinal fluid.”

Lyme disease is the most common vector-borne illness in the US, transmitted to humans and animals by ticks. In horses, symptoms can include chronic weight loss, lameness and low-grade fever.

Usually, when a Lyme disease infection is suspected, antibody tests are administered. However, in the case of an 11-year-old Swedish warmblood mare, a standard PCR and antibody test did not detect an infection. 

It was Schutzer's advanced test that ultimately detected the pathogen, allowing Lyme disease to be diagnosed and successfully treated.

Professor Thomas Divers, a veterinary surgeon who led the equine team on the paper, said: "The diagnosis of Lyme neuroborreliosis (Neurologic Lyme disease) in horses is rarely confirmed antemortem and has frustrated veterinarians for years. 

“This is a very promising technique. Focused treatment against B. burgdorferi administered in this case resulted in the horse's complete athletic recovery."

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Defra shares new Sanitary and Phytosanitary guidance

News Story 1
 Defra has published guidance for the vet sector ahead of a proposed UK-EU Sanitary and Phytosanitary agreement.

The agreement, which will change the movement and trade of animals and related products, could see reductions in checks, paperwork and certification. As well as describing regulatory developments, the advice highlights the importance of animal ID, registration and traceability in disease control and other compliance arrangements.

The guidance can be found here. More detail is expected as negotiations progress. 

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News Shorts
Lords Committee opens Pet Parasite Medication inquiry

The House of Lords Environment and Climate Change Committee will launch its inquiry into Pet Parasite Medication (PPM) on Wednesday (3 June).

Focusing on treatments containing fipronil and imidacloprid, the inquiry will seek to understand distribution pathways and the impacts of PPM use and non-use on biodiversity and human health. It will also cover current regulation, monitoring, and the potential implications for pets and their owners.

The committee will hear evidence from environmental non-governmental organisations and research institutes. The public can follow the proceedings live on Parliament TV or in person in the Palace of Westminster.