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Scientists 'step closer' to understanding syringomyelia
Scientists developed a computer model based on the MRI from a Cavalier King Charles Spaniel.
Researchers find links to Bernard Williams’ “slosh” hypothesis.

A study led by scientists at the University of Surrey has revealed new insights into the development of spinal cord disease, syringomyelia, revealing that a hypothesis developed by neurosurgeon Bernard Williams in 1980 is likely to be correct.

Syringomyelia is a painful spinal cord disease of dogs and humans characterised by fluid-filled cavities, but it is not yet fully understood exactly how these cavities are formed. 

In 1980, neurosurgeon Bernard Williams hypothesised that pressure changes resulting from sneezing and coughing caused fluid in the cavity to “slosh”, thereby placing stress on the spinal cord tissue and enabling the cavity to expand.

In this latest study, researchers from the University of Surrey's Centre for Biomedical Engineering Sciences and the School of Veterinary Medicine developed a computer model based on the MRI from a Cavalier King Charles spaniel with syringomyelia.

Through the model, the scientists were able to show that the fluid “slosh” caused a small cavity to expand gradually down the spinal cord. However, when the syrinx became large, there was less focal stress – a finding that could explain why syringomyelia can develop rapidly but then remain unchanged in shape over time. 

Looking ahead, the team plans to develop the model to improve understanding of why syringomyelia develops and to model potential surgeries for reversing the condition. Their findings are published in the journal Life.

“It has been both fascinating and challenging to work on the problem of syringomyelia over the last decade," commented Dr Srdjan Cirovic, a lecturer in biomedical engineering at the University of Surrey. "With this breakthrough, we are one step closer to understanding this puzzling neurological condition. 

He added: "In the future, we are looking towards using these findings to inform the improved medical treatment of syringomyelia in humans as well as animals.” 

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Webinar to explore history of KC breed registers

News Story 1
 A free webinar exploring the development of the Kennel Club's registration system and the evolution of closed breed registers has been announced.

Hosted by Dr Alison Skipper, veterinary and research advisor at the Kennel Club, the webinar will delve into the development of the registry and how the changing landscape of scientific knowledge has shaped breeding practices. It will also look at what this means for the future of pedigree dogs.

The session will culminate with a look at The Kennel Club's ongoing and future engagement in this area, with a chance for attendees to put forward their thoughts and questions for discussion.

This event takes place on Microsoft Teams on Tuesday, 10 June at 7pm. To learn more, visit events.teams.microsoft.com  

Click here for more...
News Shorts
UK's BSE risk status downgraded

The WOAH has downgraded the UK's international risk status for BSE to 'negligible'.

Defra says that the UK's improved risk status recognises the reputation for having the highest standards for biosecurity. It adds that it demonstrates decades of rigorous animal control.

Outbreaks of Bovine Spongiform Encephalopathy, also known as mad cow disease, have previously resulted in bans on Britain's beef exports.

The UK's new status could lead to expanded trade and better confidence in British beef.

Christine Middlemiss, the UK's chief veterinary officer, said: "WOAH's recognition of the UK as negligible risk for BSE is a significant milestone and is a testament to the UK's strong biosecurity measures and the hard work and vigilance of farmers and livestock keepers across the country who have all played their part in managing the spread of this disease.