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Puppy successfully treated for vitamin D poisoning
Miniature dachshund Margot arrived at the hospital with depression, lethargy and nausea.

Miniature dachshund Margot is recovering after devouring human psoriasis medication.

A puppy has been treated successfully for vitamin D poisoning after eating a human medicine containing a synthetic form of the supplement. 

Miniature dachshund Margot was presented to Davies Veterinary Specialists after gobbling up a tube of Dovonex ointment - a topical cream used to treat psoriasis in humans that contains
calcipotriol, a synthetic derivative of vitamin D.

“We calculated that four-month-old Margot had ingested between 500-1000µg (161µg/kg – 323µg/kg) of calcipotriol,” explained Katherine Clarke, an internal medicine resident at Davies. “Toxicity studies in dogs suggest that 1.8 to 3.6µg /kg /day of calcipotriol can cause disturbances in calcium homeostasis, so it wasn’t surprising that Margot developed evidence of toxicity.” 

Margot arrived at the veterinary hospital with depression, lethargy and nausea. She was also severely hypercalcaemic and mildly azotaemic.

The team initially managed her vitamin D poisoning with prednisolone, furosemide and intravenous fluid therapy. While she did show some clinical improvement, the hypercalcaemia persisted, prompting the addition of pamidronate to her treatment. 

The combination of the treatments resulted in normocalcaemia and resolution of the azotaemia. The furosemide was then stopped, and the intravenous fluid therapy was gradually reduced over a few days; her calcium remained normal. 

Margot was discharged on tapering doses of prednisolone and blood tests were performed before each dose reduction to ensure she remained normocalcaemic. She is now said to be be clinically very well having been off all treatment for a few months, and there are no signs that the vitamin D poisoning has led to any permanent damage. 

“Vitamin D toxicity is relatively rare, although the growing trend in vitamin D supplementation in the human population means that dogs are more likely to have access to this vitamin,” said Katherine. 

“Ingestion of psoriasis cream, either by licking it from the skin of the owner or direct ingestion by chewing the tube, is another well-recognised mechanism of vitamin D toxicity in dogs,” she continued. “The addition of vitamin D (cholecalciferol) to rodenticides is also increasing, ingestion of which would cause the undesirable combination of vitamin D toxicosis and a coagulopathy”.

“The prognosis for vitamin D toxicity is variable with some cases experiencing an acute kidney injury or severe gastrointestinal bleeding due to calcification of the soft tissues. However, with prompt, aggressive treatment the prognosis can be reasonable.”

 

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Practices urged to audit neutering data

News Story 1
 RCVS Knowledge has called on vet practices to audit their post-operative neutering outcomes.

It follows the release of the 2024 NASAN benchmarking report, which collates data from neutering procedures performed on dogs, cats and rabbits.

The benchmarking report enables practices in the UK and Ireland to compare their post-operative outcomes to the national average. This includes the rate of patients lost to follow-up, which in 2024 increased to 23 per cent.

Anyone from the practice can submit the data using a free template. The deadline for next report is February 2026.

Visit the RCVS Knowledge website to complete an audit. 

Click here for more...
News Shorts
New guidance for antibiotic use in rabbits

New best practice guidance on the responsible use of antibiotics in rabbits has been published by the BSAVA in collaboration with the Rabbit Welfare Association & Fund (RWA&F).

The guidance is free and has been produced to help veterinary practitioners select the most appropriate antibiotic for rabbits. It covers active substance, dose and route of administration all of which are crucial factors when treating rabbits owing to the risk of enterotoxaemia.

For more information and to access the guide, visit the BSAVALibrary.