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Low cholesterol linked to mortality in cats and dogs, study suggests
"These findings suggest that low cholesterol levels are associated with mortality in canine and feline patients" - Steven Epstein.
Researchers assess the period prevalence of hypocholesterolaemia and associated mortality rates.
 
Low levels of cholesterol are associated with mortality in canine and feline patients, according to new research.

The study published in the Journal of Small Animal Practice assessed the period prevalence of hypocholesterolaemia and the associated mortality rates in dogs and cats at the Veterinary Medical Teaching Hospital, University of California, Davis. 

The team reviewed medical records of cats and dogs presenting to the hospital from September 2011 to August 2016 to identify animals that had at least one cholesterol measurement. They also collated patient signalment and clinical information, before calculating the period prevalence and mortality rate of hypocholesterolaemia. 

The study revealed that the period prevalence of hypocholesterolaemia was 7 per cent in dogs and 4.7 per cent in cats. The mortality rate of hypocholesteraemic dogs and cats was 12 per cent in both species, which was significantly higher than that of animals with normal serum cholesterol. 

Steven Epstein, corresponding author for the paper, said: “The odds of death in dogs and cats with hypocholesterolaemia were 3.2 and 2.5 times higher than in those with normocholesterolaemia respectively. Furthermore, there was a significant linear trend towards higher mortality in association with more severe hypocholesterolaemia in both species.

“Disease of the hepatic, gastrointestinal and lymphoreticular systems were most commonly associated with hypocholesterolaemia, and infectious and neoplastic disease were the most commonly associated pathophysiological processes in both species. In dogs with neoplasia, lymphoma was over-represented.”

JSAP editor Nicola Di Girolamo said: “These findings suggest that low cholesterol levels are associated with mortality in canine and feline patients. It is not clear whether hypocholesterolaemia is simply a marker for disease severity, or if it has active physiological effects contributing to poor outcomes. At this stage, it seems indicated to enhance intensity of diagnostic effort and therapy for affected animals.”

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Practices urged to audit neutering data

News Story 1
 RCVS Knowledge has called on vet practices to audit their post-operative neutering outcomes.

It follows the release of the 2024 NASAN benchmarking report, which collates data from neutering procedures performed on dogs, cats and rabbits.

The benchmarking report enables practices in the UK and Ireland to compare their post-operative outcomes to the national average. This includes the rate of patients lost to follow-up, which in 2024 increased to 23 per cent.

Anyone from the practice can submit the data using a free template. The deadline for next report is February 2026.

Visit the RCVS Knowledge website to complete an audit. 

Click here for more...
News Shorts
UK's BSE risk status downgraded

The WOAH has downgraded the UK's international risk status for BSE to 'negligible'.

Defra says that the UK's improved risk status recognises the reputation for having the highest standards for biosecurity. It adds that it demonstrates decades of rigorous animal control.

Outbreaks of Bovine Spongiform Encephalopathy, also known as mad cow disease, have previously resulted in bans on Britain's beef exports.

The UK's new status could lead to expanded trade and better confidence in British beef.

Christine Middlemiss, the UK's chief veterinary officer, said: "WOAH's recognition of the UK as negligible risk for BSE is a significant milestone and is a testament to the UK's strong biosecurity measures and the hard work and vigilance of farmers and livestock keepers across the country who have all played their part in managing the spread of this disease.