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EmailIphone Application    Posted: 19th November 2020
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Novel cat genome identifies link to feline dwarfism
Scientists applied the new model to the genomes of 54 domestic cats.
Study could lead to earlier disease detection and treatments with fewer side effects. 

Researchers in the USA have discovered a genetic mutation linked to feline dwarfism with a gene not previously linked with dwarfism in any species.

Scientists at the University of Missouri and Texas A&M discovered the new variant by developing a new cat genome reference model in a bid to uncover new links between DNA mutations and feline disease. 

The model, which is part-funded by Purina, is said to be 'vastly more accurate and improves scientists’ ability to identify DNA variations that influence the health of individual cats'. 

Felines suffer from many of the same diseases that affect humans. However, the level of genetic information available to help develop new tests and treatments in humans has not been available for cats. 

To help rectify this, researchers applied the new model to 54 cat genomes to identify variations that could be the cause of disease in domestic cats. The genetic mutation linked to feline dwarfism is one of the several discoveries detailed in the journal PLOS Genetics.

Looking ahead, the team hopes to use the model to extend the use of precision medicine in feline veterinary care. The resource could enable scientists to develop more useful genetic screening tests, provide earlier disease detection, and lead to the development of improved treatments with fewer side effects.

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Birmingham Dogs Home makes urgent appeal

News Story 1
 Birmingham Dogs Home has issued an urgent winter appeal as it faces more challenges over the Christmas period.

The rescue centre has seen a dramatic increase in dogs coming into its care, and is currently caring for over 200 dogs. With rising costs and dropping temperatures, the charity is calling for urgent support.

It costs the charity £6,000 per day to continue its work.

Fi Harrison, head of fundraising and communications, said: "It's heart-breaking for our team to see the conditions some dogs arrive in. We really are their last chance and hope of survival."

More information about the appeal can be found here. 

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Avian flu confirmed at premises in Cornwall

A case of highly pathogenic avian influenza H5N1 has been detected in commercial poultry at a premises near Rosudgeon, Cornwall.

All poultry on the infected site will be humanely culled, and a 3km protection zone and 10km surveillance zone have been put in place. Poultry and other captive birds in the 3km protection zone must be housed.

The case is the second avian flu case confirmed in commercial poultry this month. The H5N5 strain was detected in a premises near Hornsea, East Riding of Yorkshire, in early November. Before then, the disease had not been confirmed in captive birds in England since February.

The UK chief veterinary officer has urged bird keepers to remain alert and practise robust biosecurity.

A map of the disease control zones can be found here.