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Blinding inherited condition found in giant schnauzers
The genetic mutation that causes PRA in giant schnauzers occurs in approximately one in 35 dogs. 
Geneticists ID genetic mutation and launch DNA test 

Scientists at the Animal Health Trust (AHT) have developed a DNA test for progressive retinal atrophy (PRA) in giant schnauzers, a previously undiagnosed condition in the breed.

PRA may initially cause dogs to lose their vision in low light at night, have difficulty seeing obstacles or finding their way in familiar surroundings. Visual impairment worsens over months or years and, eventually, all affected dogs will lose their sight.

The condition is well documented in more than 100 dog breeds but had not previously been identified in giant schnauzers.

DNA samples were sent to AHT from a litter of four-year-old giant schnauzers, two of which had previously been diagnosed with PRA. Testing confirmed one further dog from the same litter also had PRA, while the parents were clear of the disease.

This confirmed the presence of an autosomal recessive PRA, where the affected dog has to carry two copies of the PRA-causing variant to develop the disease.

Scientists were able to identify the causal mutation - a single letter change in the 2.4 billion letter DNA code. They discovered this mutation occurs in approximately one in 35 giant schnauzers.  

Research assistant Rebekkah Hitti said: “As this condition in the Giant Schnauzer is quite rare we’re not expecting to find many affected dogs through DNA testing, but it is crucial to identify any carriers in order to prevent more puppies being born with this blinding condition, and to stop it becoming more widespread in future.
 
“We’ve had a good level of interest in this research so far from Schnauzer breeders and we’re confident that this breeding community is keen to get this mutation under control, and in time, eradicate it safely from their breed altogether.”

The DNA test costs £48 and is now available from the AHT DNA Testing Service.
 

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AWF Student Grant open for submissions

News Story 1
 Applications are open for the Animal Welfare Foundation (AWF) Student Grant Scheme for innovative research projects designed to impact animal welfare.

Undergraduate and postgraduate students of veterinary science, veterinary nursing, agriculture studies and animal welfare are invited to submit their proposals to undertake research projects next year.

Grants are decided based on the project’s innovation, relevance to topical animal welfare issues and ability to contribute towards raising animal welfare standards. For more information visit animalwelfarefoundation.org.uk.  

Click here for more...
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SPANA film highlights plight of working animals overseas

Animal welfare charity SPANA (The Society for the Protection of Animals Abroad) has teamed up with Brian Blessed and other famous voices to highlight the plight of working animals overseas.

In a new animated film, the celebrities raise awareness by showing the solidarity of the UK's own working animals on strike. A sniffer dog (Brian Blessed), police horse (Peter Egan) and sheepdog (Deborah Meaden) are shown ignoring their duties and protesting in solidarity with animals in developing countries.

SPANA chef executive Geoffrey Dennis said: "We are so grateful to Deborah, Peter and Brian for lending their voices to our new film, and for speaking up for millions of working animals overseas. SPANA believes that a life of work should not mean a life of suffering, and it is only thanks to people’s generosity and support that we can continue our vital work improving the lives of these animals."