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New DNA test for glaucoma-causing mutation in border collies
“Our research has found that the mutation is only associated with glaucoma in border collies."
Scientists identify variant in the gene OLFML3 

The Animal Health Trust has launched a new DNA test for the genetic mutation that causes glaucoma in border collies.

Scientists from the Roslin Institute originally identified a variant in the gene OLFML3, which is associated with severe goniodysgenesis and glaucoma in this dog breed.

On reading the research, the Animal Health Trust’s genetics team genotyped a large cohort of border collies for the mutation, which allowed the team to obtain an accurate measure of the association between the mutation and goniodysgenesis and glaucoma. All dogs were also given an eye examination and had DNA collected.

The new test was developed and launched following this validation process, which replicated the findings from the Roslin Institute. Breeders will now be able to use the test to reduce the risk of producing puppies affected with glaucoma, which affects more than 1,000 dogs across the UK.

Dr Cathryn Mellersh, head of canine genetics at the Animal Health Trust, said: “We’re delighted to offer this test to border collie breeders and hope in time, through its use, we can lessen the prevalence of this disease in this lovely breed.
 
“Our research has found that the mutation is only associated with glaucoma in border collies, so we will publish our data at the earliest opportunity, in the hope that other commercial DNA testing providers will not be tempted to make the DNA test available to breeds other than the border collie.”

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Huge spike in ‘designer’ dogs going into rescue

News Story 1
 The RSPCA has reported a huge spike in the number of ‘designer’ dogs arriving into its care.

Figures published by the charity show there has been a 517 per cent increase in the number of French bulldogs arriving into its kennels. During that time, the charity has also seen an increase in dachshunds, chihuahuas, and crossbreeds.

RSPCA dog welfare expert Lisa Hens said: “We know that the breeds of dog coming into our care often reflect the trends in dog ownership in the wider world and, at the moment, it doesn’t get more trendy than ‘designer’ dogs like French bulldogs and Dachshunds."

 

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Withdrawal period increased for Closamectin pour-on

The withdrawal period for Closamectin pour-on solution for cattle has been increased from 28 days to 58 for meat and offal.

Closamectin treats roundworms, late immature to adult fluke (from seven weeks), mange mites and lice.

Norbrook Laboratories Ltd said the change would take effect immediately. Customers are being offered practical support to inform end users.

The change meets industry requirements to reduce the amount of residue going into food and the environment. It has been approved by the Veterinary Medicines Directorate and an updated summary of product characteristics will be available on the website.