Cookie use on MRCVSonline
We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive all cookies.
If you would like to forward this story on to a friend, simply fill in the form below and click send.

Your friend's email:
Your email:
Your name:
 
 
Send Cancel

New DNA test for glaucoma-causing mutation in border collies
“Our research has found that the mutation is only associated with glaucoma in border collies."
Scientists identify variant in the gene OLFML3 

The Animal Health Trust has launched a new DNA test for the genetic mutation that causes glaucoma in border collies.

Scientists from the Roslin Institute originally identified a variant in the gene OLFML3, which is associated with severe goniodysgenesis and glaucoma in this dog breed.

On reading the research, the Animal Health Trust’s genetics team genotyped a large cohort of border collies for the mutation, which allowed the team to obtain an accurate measure of the association between the mutation and goniodysgenesis and glaucoma. All dogs were also given an eye examination and had DNA collected.

The new test was developed and launched following this validation process, which replicated the findings from the Roslin Institute. Breeders will now be able to use the test to reduce the risk of producing puppies affected with glaucoma, which affects more than 1,000 dogs across the UK.

Dr Cathryn Mellersh, head of canine genetics at the Animal Health Trust, said: “We’re delighted to offer this test to border collie breeders and hope in time, through its use, we can lessen the prevalence of this disease in this lovely breed.
 
“Our research has found that the mutation is only associated with glaucoma in border collies, so we will publish our data at the earliest opportunity, in the hope that other commercial DNA testing providers will not be tempted to make the DNA test available to breeds other than the border collie.”

Become a member or log in to add this story to your CPD history

Big Butterfly Count returns

News Story 1
 The world's biggest survey of butterflies is back for 2020!

Butterfly Conservation's Big Butterfly Count launches on Friday, 17 July and will run until Sunday 9 August. Members of the public can get involved by downloading the Big Butterfly Count App or recording results on a downloadable sheet available from bigbutterflycount.org/.

'It's a fantastic activity for people from three to 103 years and we'd encourage everyone to take 15 minutes in an appropriate outdoor space during sunny conditions to simply appreciate the nature around them and do their bit to help us understand butterfly populations,' said a Butterfly Conservation spokesperson. 

Click here for more...
News Shorts
New appointment at Dechra

Dechra Veterinary Products Ltd (Dechra) has announced a key appointment to support veterinary professionals across Northern Ireland and the Republic of Ireland.

Karen Hockley has been appointed as a telesales account manager and will provide the latest products, news and developments from Dechra. She joins the company from a large mixed practice in Northern Ireland where she was the branch manager.

Before that, Karen had worked for a multinational veterinary pharmaceutical company as a key account manager for Northern Ireland. She can be contacted at karen.hockley@dechra.com or 087 219 54 30.