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New antibiotic compounds discovered in soil
The new compounds, named malacidins, were found in soil samples collected from across America.

Malacidins found to eliminate MRSA in rats

Researchers in America have found a new family of antibiotics that can kill drug-resistant bacteria.

The antibiotics, called malacidins, have proven successful at killing several infections that are difficult to treat, including MRSA. Researchers say that discovery, published in Nature Microbiology brings fresh hope in the fight against antibiotic resistance.

In the study, researchers collected 1,800 soil samples from sites across America and used a gene sequencing technique to study them. When they found malacidins in many of the samples, they tested them on rats with induced MRSA and it completely eliminated the infection.

Speaking to BBC News, Dr Sean Brady from Rockefeller University said that his team are now working to improve the drug’s effectiveness so that it can be developed into a treatment for humans.

“It is impossible to say when, or even if, an early stage antibiotic discovery like the malacidins will proceed to the clinic,” he said. “It is a long, arduous road from the initial discovery of an antibiotic to a clinically used entity."

Antibiotic resistance is one of the biggest threats to global health, accelerated by the overuse of antibiotics as well as poor infection prevention and control. According to the World Health Organisation, almost half a million people developed resistance to TB in 2016 and the issue is starting to complicate the fight against HIV and malaria.

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Equine Disease Surveillance report released for Q4 2025

News Story 1
 The latest Equine Disease Surveillance report has been released, with details on equine disease from Q4 of 2025.

The report, produced by Equine Infectious Disease Surveillance, includes advice on rule changes for equine influenza vaccination.

Statistics and maps detail recent outbreaks of equine herpes virus, equine influenza, equine strangles and equine grass sickness. A series of laboratory reports provides data on virology, bacteriology, parasitology and toxicosis.

This issue also features a case study of orthoflavivus-associated neurological disease in a horse in the UK. 

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News Shorts
BSAVA announces 12th Edition of the Small Animal Formulary

The BSAVA has published an updated edition of its Small Animal Formulary, which includes new drug monographs and emergency drug doses for rabbits, rodents, birds and reptiles.

One of BSAVA's most trusted and widely used clinical resources, this 12th edition of the manual also includes seven new client information leaflets and information on drugs used for the management of urinary incontinence.

Part A of the Formulary, Canine and Feline, sees Fergus Allerton return as Editor-in-Chief, while Part B: Exotic Pets was edited by Joanna Hedley. For more information, visit the BSAVA website.