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Komodo dragon blood could help in AMR fight
komodo dragon
Komodo dragon saliva contains at least 57 species of bacteria that are thought to help kill their prey, but the Komodo itself appears to be resistant to the bacteria.
Scientists identify antimicrobial activity in lizard’s blood

Antimicrobial substances discovered in the blood of Komodo dragons could help with the development of new drugs for treating antibiotic resistant infections, scientists say.

A study published in the Journal of Proteome Research describes antimicrobial protein fragments that appear to help the lizards resist deadly infections.

Komodo dragon saliva contains at least 57 species of bacteria that are thought to help kill their prey, but the Komodo itself appears to be resistant to the bacteria.

Researchers from the College of Science at George Mason University identified and sequenced 48 potential cationic antimicrobial peptides (CAMPs) - an essential part of the innate immune system - in the blood of Komodo dragons. All but one of these were derived from histone proteins, which are known to have antimicrobial activities.

Eight were synthesised and tested against Pseudomonas aeruginosa and Staphylococcus aureus. Seven out of eight showed significant potency against both bacteria and the eighth was only effective against P. aeruginosa. The researchers conclude that Komodo blood plasma contains a host of potentially viable antimicrobial peptides that could lead to new treatments.

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Defra shares new Sanitary and Phytosanitary guidance

News Story 1
 Defra has published guidance for the vet sector ahead of a proposed UK-EU Sanitary and Phytosanitary agreement.

The agreement, which will change the movement and trade of animals and related products, could see reductions in checks, paperwork and certification. As well as describing regulatory developments, the advice highlights the importance of animal ID, registration and traceability in disease control and other compliance arrangements.

The guidance can be found here. More detail is expected as negotiations progress. 

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News Shorts
New form for online veterinary medicines retailers

The Veterinary Medicines Directorate (VMD) has produced a new online form for retailers wishing to sell veterinary medicines on the internet.

The form replace the previous Word version and is part of the VMD's ongoing commitment to digitise its processes. Anyone retailing prescription medicines online, including POM-V, POM-VPS and NFA-VPS categories, is lawfully required to register with the VMD before trading.

The change only applies to new applicants. Retailers already listed on the VMD's Register of Online Retailers or registered under the Accredited Internet Retailer Scheme (AIRS) do not need to do anything.