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Horse study unlocks clues to ageing tendons
Horse tendons
Damaged tendons in younger horses were found to contain more of the proteins used in healing than the damaged samples from old horses, suggesting that healing also slows with age.
The study opens up the possibility of better treatment for humans

Scientists from the University of Liverpool have examined the mechanisms that cause ageing in the tendons of horses, opening up the possibility of better treatment for humans.

The study used samples taken from young and old horses, which have similar tendon properties to those in human beings. Researches performed a range of tests to profile the types, quantities and proportions of proteins present in the tendon.

The scientists discovered marked differences in the proteins in young and old horses. Professor Peter Clegg, chair of musculoskeletal biology, explains: "Injured tendons are extremely painful and limiting in humans and we know that this increases as we get older.

"We're now starting to get to the 'why' of this process by showing that the proteins produced by the cells to repair damage alter as we get older."

The research also found that certain fragments of protein appear in greater quantities in older horses, suggesting that they are released as the tissue is damaged over time.

In comparison, damaged tendons in younger horses were found to contain more of the proteins used in healing than the damaged samples from old horses. This suggests that healing also slows with age.

Professer Clegg added: "This now opens up the possibility of better treatment and prevention strategies to address tendon injuries in both man and veterinary specifies such as the horse."

The study, ‘Proteomic analysis reveals age-related changes in tendon matrix composition, with age-and injury-specific matrix fragmentation’, was published in the Journal of Biological Chemistry.

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Webinar to explore history of KC breed registers

News Story 1
 A free webinar exploring the development of the Kennel Club's registration system and the evolution of closed breed registers has been announced.

Hosted by Dr Alison Skipper, veterinary and research advisor at the Kennel Club, the webinar will delve into the development of the registry and how the changing landscape of scientific knowledge has shaped breeding practices. It will also look at what this means for the future of pedigree dogs.

The session will culminate with a look at The Kennel Club's ongoing and future engagement in this area, with a chance for attendees to put forward their thoughts and questions for discussion.

This event takes place on Microsoft Teams on Tuesday, 10 June at 7pm. To learn more, visit events.teams.microsoft.com  

Click here for more...
News Shorts
UK's BSE risk status downgraded

The WOAH has downgraded the UK's international risk status for BSE to 'negligible'.

Defra says that the UK's improved risk status recognises the reputation for having the highest standards for biosecurity. It adds that it demonstrates decades of rigorous animal control.

Outbreaks of Bovine Spongiform Encephalopathy, also known as mad cow disease, have previously resulted in bans on Britain's beef exports.

The UK's new status could lead to expanded trade and better confidence in British beef.

Christine Middlemiss, the UK's chief veterinary officer, said: "WOAH's recognition of the UK as negligible risk for BSE is a significant milestone and is a testament to the UK's strong biosecurity measures and the hard work and vigilance of farmers and livestock keepers across the country who have all played their part in managing the spread of this disease.