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Researchers find pig gene needed for ASF virus
ASF is a fast-acting and severe virus which causes widespread illness and death.

The gene may lead to development of pigs resistant to infection.

Researchers have identified a gene in pigs’ DNA which is needed for African Swine Fever (ASF) to replicate.

The discovery of this gene, which is involved in the pig immune system, could lead to the development of pigs that are resistant to ASF.

ASF is a fast-acting and severe virus which causes widespread illness and death, and has caused high losses for the pork industry.

The infection has already killed more than 200 million pigs worldwide, and is currently a major issue across Asia. It has the potential to cause outbreaks in Europe and America.

There is currently no vaccine or treatment available.

The finding raises the potential of amending the gene, using gene editing, to develop ASF-resistant pigs.

The research was led by the Friedrich-Loeffler Institute in Germany alongside the Roslin Institute, which is part of the University of Edinburgh’s Royal (Dick) School of Veterinary Studies.

The researchers examined a collection of pig cells, with each cell edited to lack a specific gene, to investigate how they responded to the ASF virus.

This analysis identified a suite of genes, known as the MHC-II complex, which produce proteins that are associated with the immune response to infections that were key to the virus.

This led them to a single protein in the MHC-II complex known as SLA-DM, which was essential to the replication of the virus in the cells.

The group hopes that editing this gene may allow for the development of pigs which are resistant to ASF, to mitigate the impact of the virus.

They believe that further research should aim to understand the biological processes in which SLA-DM proteins and virus particles interact.

Dr Finn Grey, of the Roslin Institute, said: “Our study identifies target genes for editing to develop pigs resistant to African Swine Fever.

“Although more work is required, this finding represents an important first step towards the generation of ASF-resistant pigs.”

The full study can be found in the Scientific Reports journal.

Image © Shutterstock

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Equine Disease Surveillance report released for Q4 2025

News Story 1
 The latest Equine Disease Surveillance report has been released, with details on equine disease from Q4 of 2025.

The report, produced by Equine Infectious Disease Surveillance, includes advice on rule changes for equine influenza vaccination.

Statistics and maps detail recent outbreaks of equine herpes virus, equine influenza, equine strangles and equine grass sickness. A series of laboratory reports provides data on virology, bacteriology, parasitology and toxicosis.

This issue also features a case study of orthoflavivus-associated neurological disease in a horse in the UK. 

Click here for more...
News Shorts
RCVS annual renewal fee for vets due

RCVS' annual renewal fee for veterinary surgeons is now due. Vets must pay their renewal fee before Wednesday, 1 April 2026.

This year's standard annual fee has increased to 431 from last year's 418. This is an approximately three per cent increase, as approved by RCVS Council and the Privy Council.

Tshidi Gardner, RCVS treasurer, said: "The small fee increase will be used to help deliver both our everyday activities and our new ambitious Strategic Plan, which includes aims such as achieving new legislation, reviewing the Codes of Professional Conduct and supporting guidance, and continuing to support the professions through activities such as the Mind Matters Initiative, RCVS Academy and career development."

A full breakdown of the new fees is on the RCVS website. Information about tax relief is available on the UK government website.