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Toxoplasmosis cases declining in high-income countries
People can become infected with toxoplasmosis by eating food or drinking water contaminated with parasites shed in the faeces of infected cats.

Researchers identify changing epidemiology of this harmful foetal disease.

Human toxoplasmosis rates have been declining in high-income countries over the past six decades, according to new research.

However, an epidemiological "peak shift" - where more women contract the disease for the first time during pregnancy rather than before motherhood - can cause transient spikes in high prevalence countries.

The study by the Royal Veterinary College (RVC) and published in the journal Trends in Parasitology analysed six decades of data from more than a quarter of a million people from 19 countries. 

As well as highlighting the changing epidemiology of toxoplasmosis, the study also found gaps in the current understanding of the parasite Toxoplasma gondii (T. gondii) in low- and middle-income countries, and calls for this to be addressed in future research.

It also suggests that pregnant women from countries predicted to experience a rise in cases may benefit from the introduction of temporary screening programmes and a reassessment of the cost-effectiveness of these programmes to consider related disorders.

RVC lead researcher and postdoctoral scientist Dr Gregory Milne said: “Toxoplasma causes a large public health burden, from severe congenital disease among infants, to fatal infections among people with compromised immune systems, to other more subtle changes in host behaviour. It is therefore promising news to find consistent evidence of decreases in parasite exposure in many populations and countries. 

“We show that more data are needed to assess the trajectories of exposure trends in lower-income countries. Our findings nonetheless caution against complacency: in high-prevalence countries, despite decreasing parasite exposure, cases of congenital disease may counterintuitively increase as more women acquire primary infections in pregnancy.”

Toxoplasmosis affects some 190,000 pregnancies globally every year and occurs when pregnant women become infected with the parasite T. gondii for the first time, passing the infection to the foetus. Of the 19,000 annually reported cases, three per cent of infected infants die before one month of age, sometimes before birth, and those who survive can experience issues with their vision and development.

Around one-third of the human population is thought to have been exposed to T.gondii. People can become infected by eating food or drinking water contaminated
 with parasites shed in the faeces of infected cats. 

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Webinar to explore history of KC breed registers

News Story 1
 A free webinar exploring the development of the Kennel Club's registration system and the evolution of closed breed registers has been announced.

Hosted by Dr Alison Skipper, veterinary and research advisor at the Kennel Club, the webinar will delve into the development of the registry and how the changing landscape of scientific knowledge has shaped breeding practices. It will also look at what this means for the future of pedigree dogs.

The session will culminate with a look at The Kennel Club's ongoing and future engagement in this area, with a chance for attendees to put forward their thoughts and questions for discussion.

This event takes place on Microsoft Teams on Tuesday, 10 June at 7pm. To learn more, visit events.teams.microsoft.com  

Click here for more...
News Shorts
UK's BSE risk status downgraded

The WOAH has downgraded the UK's international risk status for BSE to 'negligible'.

Defra says that the UK's improved risk status recognises the reputation for having the highest standards for biosecurity. It adds that it demonstrates decades of rigorous animal control.

Outbreaks of Bovine Spongiform Encephalopathy, also known as mad cow disease, have previously resulted in bans on Britain's beef exports.

The UK's new status could lead to expanded trade and better confidence in British beef.

Christine Middlemiss, the UK's chief veterinary officer, said: "WOAH's recognition of the UK as negligible risk for BSE is a significant milestone and is a testament to the UK's strong biosecurity measures and the hard work and vigilance of farmers and livestock keepers across the country who have all played their part in managing the spread of this disease.