Your data on MRCVSonline
The nature of the services provided by Vision Media means that we might obtain certain information about you.
Please read our Data Protection and Privacy Policy for details.

In addition, (with your consent) some parts of our website may store a 'cookie' in your browser for the purposes of
functionality or performance monitoring.
Click here to manage your settings.
If you would like to forward this story on to a friend, simply fill in the form below and click send.

Your friend's email:
Your email:
Your name:
 
 
Send Cancel

MRSA arose in nature before human and livestock use of antibiotics
Up to 60 per cent of hedgehogs carry a type of MRSA called mecC-MRSA.

Hedgehogs have carried the superbug long before human antibiotic use. 

Scientists at the University of Cambridge, along with other international institutions, have discovered that a type of MRSA arose in hedgehogs and existed in nature 200 years before the use of antibiotics in humans and livestock.

Human and livestock use of antibiotics has traditionally been blamed for the emergence of the antibiotic resistant superbug, however, these new findings suggest that the initial emergence of MRSA was a natural biological process. 

Hedgehog surveys from Denmark and Sweden discovered that up to 60 per cent of hedgehogs carry a type of MRSA called mecC-MRSA, while high levels of MRSA were discovered on hedgehogs across Europe and New Zealand. 

Senior author of the study, Dr Ewan Harrison, said: “Using sequencing technology we have traced the genes that give mecC-MRSA its antibiotic resistance all the way back to their first appearance, and found they were around in the nineteenth century.

“Our study suggests that it wasn’t the use of penicillin that drove the initial emergence of MRSA, it was a natural biological process. We think MRSA evolved in a battle for survival on the skin of hedgehogs, and subsequently spread to livestock and humans through direct contact.”

The current thinking is that this antibiotic resistance evolved in Staphylococcus aureus as an adaptation to existing alongside the fungus Trichophyton erinacei on the skin of hedgehogs, which produces its own antibiotics.

Professor Mark Holmes, senior author of the report and researcher at the University of Cambridge, commented on how the study supports careful use of antibiotics to lessen the significant threat to human health that MRSA poses: “This study is a stark warning that when we use antibiotics, we have to use them with care. 

“There’s a very big wildlife ‘reservoir’ where antibiotic-resistant bacteria can survive – and from there it’s a short step for them to be picked up by livestock, and then to infect humans.” 

Dr Sophie Lund Rasmussen of WildCRU, University of Oxford, and co-author of the study explains: "Even though this finding is news to us, the hedgehogs have carried this bacterium for at least 200 years without causing any major infections in humans.

"Therefore, the advice is as always, to appreciate and support the hedgehogs entering your garden and to maintain a good hand hygiene when feeding and possibly handling hedgehogs. Both for the sake of the hedgehogs and ourselves."

Published in Nature, the study 'Emergence of methicillin resistance predates the clinical use of antibiotics' is a collaborative effort including the University of Cambridge, the Wellcome Sanger Insitute, Denmark's Serum Statens Institut and the Royal Botanic Gardens, Kew, and is free-to-access. 

Become a member or log in to add this story to your CPD history

World Bee Day celebrations begin

News Story 1
 Today (20 May) marks the fifth annual World Bee Day, which raises awareness of the importance of bees and pollinators to people and the planet. Observed on the anniversary of pioneering Slovenian beekeeper Anton Jana's birthday, this year's celebration is themed: 'Bee Engaged: Celebrating the diversity of bees and beekeeping systems'.

Organisations and people celebrating the day will raise awareness of the accelerated decline in pollinator diversity, and highlight the importance of sustainable beekeeping systems and a wide variety of bees. Slovenia, the initiator of World Bee Day, will be focusing on teaching young people about the significance of pollinators. 

Click here for more...
News Shorts
Further avian flu cases confirmed

Three cases of highly pathogenic avian influenza (HPAI) H5N1 have been confirmed in recent days, bringing the total number of cases in England to 98.

On Thursday, the APHA confirmed two cases of HPAI H5N1 near Redgrave, Mid Suffolk and Market Weston, West Suffolk. A case H5N1 was also confirmed in poultry at a premises near Southwell, Newark and Sherwood, Nottinghamshire.

Protection and surveillance zones are in place around the affected premises. Further details are available at gov.uk