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Researchers discover new gene defect that affects muzzle length in dogs
The American Staffordshire terrier (pictured) was one of the breeds found to possess both the normal and variant forms of the gene.

DLV2 variant may also affect development of the heart.

A recent study from the University of Helsinki has revealed new insights into the impact of a DVL2 gene defect on canine health. This gene variant is already associated with a screw tail and has become widespread in English bulldogs, French bulldogs and Boston terriers as a result of inbreeding.

Julia Niskanen from the University of Helsinki and the Folkhälsan Research Center said: “In this study, we wanted to further investigate the frequency of the DVL2 variant in different dog breeds and determine its effects on skeletal development.

The DVL2 variant was identified in all of the English bulldogs, French bulldogs and Boston terriers in the study, however, both the variant and the normal form were found in the American Staffordshire terriers, Staffordshire bull terriers, dogues de Bordeaux, olde English bulldogs and American bulldogs.

Using computed tomography scans, researchers analysed the skeletal anatomy of American Staffordshire bull terriers of different genotypes, in order to determine the effect of the variant gene on body shape. They found that the presence of the DVL2 gene defect commonly resulted in caudal vertebrae 'anomalies'.

“Tail abnormalities in the American Staffordshire terriers were less severe than the screw tails typically seen in English bulldogs, French bulldogs and Boston terriers,” added Vilma Reunanen from the University of Helsinki's Faculty of Veterinary Medicine.

“In contrast to the previous study, we did not find an association between the DVL2 variant and thoracic vertebral anomalies.”

Researchers also found that the muzzles of dogs that carry two copies of the gene defect are significantly shorter. Similarly, dogs with one copy of the defect have shorter muzzles than dogs that don’t carry any copies of the gene defect.

Several of the dogs with two copies DVL2 variant were found to have a congenital heart defect. However, researchers state that this finding requires further study.

Many of the breeds that carry the DVL2 variant also have other genetic variants that affect body shape. The study affirmed that the combined effects of these defects may result in 'serious health problems'.

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VetCT app offered to students and new graduates

News Story 1
 The VetCT app is being offered for free to students and new veterinary graduates for their first three months in practice. The app provides a service for vets to send case information to a global team of Diploma-holding specialists, who can provide advice and support via instant call-back, text chat, written report, or virtual appointment.

Time on the app is automatically logged as CPD with quarterly certificates being generated for users. Additional services include the ability to book bespoke CPD, significant event reviews, and live training sessions such as surgical procedures.

The app is downloadable for both iOS and Android systems. 

Click here for more...
News Shorts
HORIBA to host CPD webinar

HORIBA has announced that it will host an online CPD meeting focusing on 'Exotic Parasites - The Importance of Testing in The Imported Dog'. Ian Wright (BVMS, MSc, MRCVS), head of ESCCAP UK and Ireland, will present on the importance of testing protocols in diseases of imported dogs.

The meeting will provide attendees with an overview of emerging veterinary diseases with a particular focus on exotic parasites, and discuss the importance of accurate testing protocols and equipment, alongside a final Q&A session.

The webinar will take place on Thursday July 1, from 19.30pm to 21.00pm BST. For free registration and more information visit the Horiba website or register.gotowebinar.com