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Novel cat genome identifies link to feline dwarfism
Scientists applied the new model to the genomes of 54 domestic cats.
Study could lead to earlier disease detection and treatments with fewer side effects. 

Researchers in the USA have discovered a genetic mutation linked to feline dwarfism with a gene not previously linked with dwarfism in any species.

Scientists at the University of Missouri and Texas A&M discovered the new variant by developing a new cat genome reference model in a bid to uncover new links between DNA mutations and feline disease. 

The model, which is part-funded by Purina, is said to be 'vastly more accurate and improves scientists’ ability to identify DNA variations that influence the health of individual cats'. 

Felines suffer from many of the same diseases that affect humans. However, the level of genetic information available to help develop new tests and treatments in humans has not been available for cats. 

To help rectify this, researchers applied the new model to 54 cat genomes to identify variations that could be the cause of disease in domestic cats. The genetic mutation linked to feline dwarfism is one of the several discoveries detailed in the journal PLOS Genetics.

Looking ahead, the team hopes to use the model to extend the use of precision medicine in feline veterinary care. The resource could enable scientists to develop more useful genetic screening tests, provide earlier disease detection, and lead to the development of improved treatments with fewer side effects.

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Defra shares new Sanitary and Phytosanitary guidance

News Story 1
 Defra has published guidance for the vet sector ahead of a proposed UK-EU Sanitary and Phytosanitary agreement.

The agreement, which will change the movement and trade of animals and related products, could see reductions in checks, paperwork and certification. As well as describing regulatory developments, the advice highlights the importance of animal ID, registration and traceability in disease control and other compliance arrangements.

The guidance can be found here. More detail is expected as negotiations progress. 

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News Shorts
Lords Committee opens Pet Parasite Medication inquiry

The House of Lords Environment and Climate Change Committee will launch its inquiry into Pet Parasite Medication (PPM) on Wednesday (3 June).

Focusing on treatments containing fipronil and imidacloprid, the inquiry will seek to understand distribution pathways and the impacts of PPM use and non-use on biodiversity and human health. It will also cover current regulation, monitoring, and the potential implications for pets and their owners.

The committee will hear evidence from environmental non-governmental organisations and research institutes. The public can follow the proceedings live on Parliament TV or in person in the Palace of Westminster.