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DNA discovery could help treat Marek's disease
Scientists identified regions of chicken DNA that are seen to play a role in disease resistance.
Scientists identify genetic regions in chickens associated with resistance.

Researchers at the University of Edinburgh's Roslin Institute have identified regions of chicken DNA associated with resistance to Marek's disease.

Scientists say the discovery, reported in the journal Genes, could pave the way to new therapies or techniques to manage the condition, which costs the global poultry industry some US$ 2 billion every year.The findings also reveal details behind susceptibility to the virus, which could lead to more precise selective breeding strategies.

“Marek’s disease is devastating to flocks worldwide as well as the economy, and current vaccination can only partially control it,” explains Dr Jaqueline Smith, study lead at the Roslin Institute.“Our study identifies regions of the genome associated with resistance, which could be used for mitigating the effects of the virus through selective breeding, improved vaccine design, or future gene-editing technologies.”

In the study, scientists identified regions of chicken DNA that are seen to play a role in disease resistance. Their approach included comparing the DNA of two groups of commercial egg-laying chickens which differed in their resistance to Marek’s disease virus.

The team analysed genetic information from infected chicks and identified variations associated with resistance in the DNA of multiple commercial chicken lines. They also investigated the genetic association with mortality in the infected offspring of egg-laying birds.

Outcomes from this research are the first to provide such a large-scale, high-resolution analysis of genes underlying resistance to the virus in birds relevant to the poultry industry.

Because the tumours caused by Marek’s disease virus have similarities to human lymphoma, researchers hope that their findings may also be able to increase understanding of human cancers.

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Webinar to share tips on impactful consultations

News Story 1
 A webinar to help veterinary professionals communicate more effectively with their clients is set to be hosted by the World Small Animal Veterinary Association (WSAVA).

Taking place on Thursday 30 September, 'Top Tips for Impactful Consultations' will be led by Suzanne Rogers, co-director of Human Behaviour Change for Animals and Dr Natasha Lee, chair of the WSAVA's Animal Wellness and Welfare Committee.

For more information about the webinar, click here

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News Shorts
New online CPD otitis podcast created

A new 15 minute podcast on treating animals with otitis has been created by Dechra Veterinary Products. Featuring general practice vet Carolyn Kyte and veterinary dermatology specialist Natalie Barnard, the two vets will discuss their experiences treating otitis, and why owners are significant in successful treatment.

Dechra Brand Manager Carol Morgan commented: "What Carolyn and Natalie bring to the table with their new podcast for the Dechra Academy is a light and insightful discussion about communication and education being the keystone for better otitis outcomes and how vets can improve on their consultation skills to handle cases better."`

The podcast, called 'Think Differently about Otitis', is available to access for free on the Dechra Academy on-demand learning platform here.