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DNA discovery could help treat Marek's disease
Scientists identified regions of chicken DNA that are seen to play a role in disease resistance.
Scientists identify genetic regions in chickens associated with resistance.

Researchers at the University of Edinburgh's Roslin Institute have identified regions of chicken DNA associated with resistance to Marek's disease.

Scientists say the discovery, reported in the journal Genes, could pave the way to new therapies or techniques to manage the condition, which costs the global poultry industry some US$ 2 billion every year.The findings also reveal details behind susceptibility to the virus, which could lead to more precise selective breeding strategies.

“Marek’s disease is devastating to flocks worldwide as well as the economy, and current vaccination can only partially control it,” explains Dr Jaqueline Smith, study lead at the Roslin Institute.“Our study identifies regions of the genome associated with resistance, which could be used for mitigating the effects of the virus through selective breeding, improved vaccine design, or future gene-editing technologies.”

In the study, scientists identified regions of chicken DNA that are seen to play a role in disease resistance. Their approach included comparing the DNA of two groups of commercial egg-laying chickens which differed in their resistance to Marek’s disease virus.

The team analysed genetic information from infected chicks and identified variations associated with resistance in the DNA of multiple commercial chicken lines. They also investigated the genetic association with mortality in the infected offspring of egg-laying birds.

Outcomes from this research are the first to provide such a large-scale, high-resolution analysis of genes underlying resistance to the virus in birds relevant to the poultry industry.

Because the tumours caused by Marek’s disease virus have similarities to human lymphoma, researchers hope that their findings may also be able to increase understanding of human cancers.

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BEVA gives RVNs right to vote

News Story 1
 The British Equine Veterinary Association (BEVA) is to allow its registered veterinary nurse (RVN) members the right to vote.

RVN members will now be able to take part in key decision-making processes and stand for BEVA council.

Marie Rippingale, chair of BEVA's Nurse Committee, said: "I am very proud to be a part of BEVA.

"This change will help to empower nurses to speak up and contribute, but more importantly, it will give them an opportunity to collaborate with other members of the equine veterinary profession to bring about change that is positive for all." 

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Northern Ireland chief vet warns of bluetongue risk

Following the detection of bluetongue virus serotype 3 (BTV-3) in England, Northern Ireland's chief veterinary officer has urged farmers to remain vigilant and source animals responsibly.

Brian Dooher said: "This confirmation in England is a stark reminder of the threat bluetongue presents to Northern Ireland.Whilst this finding in Norfolk is disappointing it is not unexpected giving the rising level of disease across several countries in Europe. Bluetongue does not affect human health or food safety, however an incursion to Northern Ireland would have a significant impact on livestock and the rural economy.

"I would like to remind all farmers of the importance of sourcing animals responsibly and ask that they maintain vigilance for signs of the disease reporting any suspicions to DAERA immediately."

Suspected cases of BTV-3 in Northern Ireland should be reported to the DAERA Helpline on 0300 200 7840 or by contacting the local DAERA Direct Veterinary Office.