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Scientists map genome of healthy German shepherd
Researchers have mapped the whole genome of a healthy German shepherd.

Tool will allow researchers to determine whether dogs are likely to develop hip dysplasia

Researchers have mapped the entire genome of a healthy German shepherd, giving vets a powerful tool with which to better screen for hip dysplasia and other canine diseases.

Scientists from the University of New South Wales (UNSW) and other institutes used advanced genome sequencing technology to unravel 38 pairs of dog chromosomes, to decode the 19,000 genes and 2.8 billion pairs of DNA.

The study was carried out on a sample of blood provided by 'Nala', a healthy five-year-old German shepherd living in Sydney, and published in the journal GigaScience.

“One of the most common health problems affecting German shepherds is canine hip dysplasia, which is a painful condition that can restrict their mobility,” explained study author Professor Bill Ballard, an evolutionary biologist at the UNSW.

“Because German shepherds make such good working dogs, there has been a lot of money spent looking into the causes and predictors of this problem. When working dogs – such as those trained to work with police or to help people with disabilities – end up getting hip dysplasia, then that’s a lot of lost time and money that has gone into the training of that dog."

He continued: “Now that we have the genome, we can determine much earlier in life whether the dog is likely to develop the condition. And over time, it will enable us to develop a breeding program to reduce hip dysplasia in future generations.”

Nala is described in the paper as “an easy-going and approachable 5.5-year-old,” selected because she was free of all known genetic diseases, including no sign of hip dysplasia. She was chosen for the study by TV and radio vet Dr Robert Zammit, who Professor Ballard says has amassed X-rays and blood samples of more than 600 German shepherds.

“Now we’ll be able to look at those hip x-rays and all the DNA of those dogs and compare them back to this healthy reference female,” Professor Ballard says. 

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Do you know a practice wellbeing star?

News Story 1
 Has someone in your practice team gone above and beyond to make your workplace a positive one during the coronavirus pandemic? Then why not nominate them for a 2020 Practice Wellbeing Star!

The joint RCVS Mind Matters Initiative/SPVS Practice Wellbeing Star nominations recognise individuals who have held up morale during a time when practices are facing unprecedented staffing and financial issues.

Nominees receive a certificate in recognition of their colleagues' appreciation of their achievements and will be entered into the prize draw for a pair of tickets to attend the joint SPVS and Veterinary Management Group Congress in January 2021.

 

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WellVet reopens ticket sales to online conference platform

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The day-long conference saw more than 360 veterinary professionals mix activity sessions with personal development CPD, all hosted within a virtual conference platform. Now, with more than 500 minutes of CPD available, the resource is being re-opened to allow full access to the session recordings until May 2021.

Sessions are aimed at providing delegates with a range of proactive wellbeing tools to explore to find ways of improving their mental and physical health. Tickets are limited in number and on sale at wellvet.co.uk until 30th August 2020.