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Hope for rapid equine influenza test
“Preventing a new influenza pandemic requires both vaccination and antiviral drugs to be administered within 48 hours of the infection."
Scientists say dipstick test could offer results in seconds 

A simple dipstick test could offer a rapid, non-invasive method of screening for equine influenza.

Iceni Diagnostics has a patent for its approach to detecting and distinguishing between human and avian flu. The company believes that with a slight modification, the test could be used for routine screening in horses before they travel to race meets and other gatherings.

Professor Robert Field, co-founder at Iceni, said 90 per cent of infections use carbohydrate recognition to bind with targets in humans and animals. This mechanism is specific to each strain of flu, so it can be used as a sensor for the disease.

“Our sensor uses sugars tagged with inexpensive gold nanoparticles,” he explained. “If the virus is present it will stick to the particles, pulling them closer together. This creates a photophysics reaction and the sample changes colour.

“We have found that there are differences between the carbohydrate detectors in the different types of flu. It is therefore possible to use a colour change to identify presence and absence of the virus and to distinguish between them.”

Using sugars instead of more commonly used protein-based diagnostics avoids the need for cold storage, meaning the test can be used worldwide with minimal training, and gives results in seconds.

According to Professor David Russell, chief scientist at Iceni, the new assay based on gold nanoparticles is much faster than current tests.

“Preventing a new influenza pandemic requires both vaccination and antiviral drugs to be administered within 48 hours of the infection in order to contain the disease,” he said.

“Current methods of detection require isolation and culturing of the virus, which may take several hours or even days to get the results. Using our test it would be possible to quickly identify infected animals at the stables and quarantine them, preventing the spread of disease.”

Iceni is now looking for investment to modify its sensor to produce a dip test for equine flu.

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Huge spike in ‘designer’ dogs going into rescue

News Story 1
 The RSPCA has reported a huge spike in the number of ‘designer’ dogs arriving into its care.

Figures published by the charity show there has been a 517 per cent increase in the number of French bulldogs arriving into its kennels. During that time, the charity has also seen an increase in dachshunds, chihuahuas, and crossbreeds.

RSPCA dog welfare expert Lisa Hens said: “We know that the breeds of dog coming into our care often reflect the trends in dog ownership in the wider world and, at the moment, it doesn’t get more trendy than ‘designer’ dogs like French bulldogs and Dachshunds."

 

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News Shorts
Withdrawal period increased for Closamectin pour-on

The withdrawal period for Closamectin pour-on solution for cattle has been increased from 28 days to 58 for meat and offal.

Closamectin treats roundworms, late immature to adult fluke (from seven weeks), mange mites and lice.

Norbrook Laboratories Ltd said the change would take effect immediately. Customers are being offered practical support to inform end users.

The change meets industry requirements to reduce the amount of residue going into food and the environment. It has been approved by the Veterinary Medicines Directorate and an updated summary of product characteristics will be available on the website.