Your data on MRCVSonline
The nature of the services provided by Vision Media means that we might obtain certain information about you.
Please read our Data Protection and Privacy Policy for details.

In addition, (with your consent) some parts of our website may store a 'cookie' in your browser for the purposes of
functionality or performance monitoring.
Click here to manage your settings.
If you would like to forward this story on to a friend, simply fill in the form below and click send.

Your friend's email:
Your email:
Your name:
Send Cancel

Inherited dog disorders 'more widespread than thought'
english springer
One in six dogs in the study carried at least one of the tested risk variants in their genome. (stock photo)
International team carries out the most comprehensive study yet
Inherited disorders in dogs may be more widespread than previously thought, according to a new international study.

Scientists from Genoscoper Laboratories Oy, in Finland, led the research in partnership with the University of Helsinki and the University of Pennsylvania. Their study is the most comprehensive of its kind to date.

The team utilised genetic panel screening to test just under 7,000 purebred dogs across around 230 breeds, for their predisposition to nearly 100 genetic disorders.

According to findings published in PLOS ONE, the researchers found 15 genetic variants known to be linked with disease in 34 dog breeds where they have not previously been documented in peer-reviewed literature.

One in six dogs in the study carried at least one of the tested risk variants in their genome, and one in six of the genetic variants tested were found in dog breeds that had not been reported to carry them before. Furthermore, the team say that several mutations often, but not always, caused the same condition in the additional breeds.

Senior author Dr Hannes Lohi from the University of Helsinki, said: "We noted that surprisingly many canine inherited disorders are actually more widespread than indicated by their original discovery studies, which opens up the door for several future scientific investigations."

Researchers believe their work provides support for the use of DNA multiplex screening for canine hereditary disorders, which represents 'a reliable and powerful discovery and utility tool for applications in veterinary diagnostics, genetic research and sustainable breeding.'

While stressing the importance of complex DNA-based information in progressing the health of purebred dogs, the authors added that this should be used alongside other established approaches.

Become a member or log in to add this story to your CPD history

Webinar to explore the meaning of veterinary leadership

News Story 1
 The WSAVA has announced a free webinar exploring the meaning of veterinary leadership in the 21st century.

Taking place at noon on Tuesday, October 19, the webinar will explore the role of veterinary professionals in leading on animal welfare, the leadership competencies required of all veterinary professionals, and the effects of leadership style on teams.

The webinar, which ends with a Q&A session, will be moderated be WSAVA President Dr Siraya Chunekamrai and led by Veterinary Management Group President Richard Casey. For more information and to access the event, click here

Click here for more...
News Shorts
Horiba announces veterinary haematology webinar

Horiba Medical has announced a free webinar providing practical insight on best practice in veterinary haematology. Entitled 'In practice haematology - Beyond the pale!' the webinar will be presented by Ronnie Barron from the University of Glasgow Veterinary School.

Ronnie's presentation, which will conclude with a Q&A session, will look at QC and artefacts of sample quality and review the effects of different pathologies. Using images, photomicrographs and video links, he will also explain the techniques and equipment needed to complement analytical automation to confirm results quality.

The webinar takes place on Thursday, October 28 (7.30-9pm). For more details and to register, click here.