Cookie use on MRCVSonline
We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive all cookies.
If you would like to forward this story on to a friend, simply fill in the form below and click send.

Your friend's email:
Your email:
Your name:
 
 
Send Cancel

Scientists discover new ‘jumping’ superbug gene
“In treatments, if colistin does not work, it literally could mean death for patients. If colistin resistance spreads, a lot of people will die.”
mcr-9 can cause resistance to colistin 

US food scientists have discovered mcr-9, a new ‘jumping gene’ that can cause resistance to the last resort antibiotic colistin.

Cornell University researchers found mcr-9 in the genome of a strain of salmonella. To their surprise, the salmonella strain did not show colistin resistance.

However, when the gene was inserted into a non-pathogenic strain of E coli, researchers were able to ‘turn on’ mcr-9, making the strain resistant to colistin.

The findings have been published in the journal Mbio.

Co-lead author Laura Carroll said: “When we originally tested the salmonella isolate and found that it wasn’t resistant to colistin, we were perplexed. But when [co-lead author Ahmed Gabella] cloned it into an E. coli host, he was able to find that the gene could confer resistance to colistin.”

Commenting on the findings, Professor Martin Wiedmann said: “In treatments, if colistin does not work, it literally could mean death for patients. If colistin resistance spreads, a lot of people will die.”

mcr-9 is the latest in a string of ‘mobilised colistin-resistance genes’ first discovered in 2015.

The National Centre for Biotechnology Information added details of the new gene to its database, so that it can be used to identify the gene in bacteria isolated from food and people.

Become a member or log in to add this story to your CPD history

Endangered turtles rescued from smugglers

News Story 1
 A group of endangered turtles have found a new home at London Zoo after being rescued from smugglers.

The four big-headed turtles arrived at the zoo at the end of last year, after smugglers tried to illegally import them to Canada, labelled as toys.

One of the turtles, named Lady Triệu after a Vietnamese warrioress, has moved to a new exhibit in the zoo’s reptile house. She is the only one of her kind in a UK zoo.

Big-headed turtles have such large heads that they cannot pull them back into their shells. To compensate, they have armour plating from head to tail and a very sharp beak to fend off predators. They are ranked number 18 on ZSL’s EDGE of Existence reptile list, which puts threatened species at the forefront of conservation action. Image © ZSL  

Click here for more...
News Shorts
Professor Abdul Rahman announced as keynote speaker for BVA Members’ Day 2019

Celebrated Indian vet and parasitologist Professor Abdul Rahman is set to deliver the keynote speech at BVA Members’ Day 2019.

Professor Rahman will present his insights into the human behaviour challenges of controlling zoonotic disease in his talk: ‘A One Health approach to rabies elimination in Asia’. The talk will outline efforts to gain political support for dog vaccination programmes in China, as well as the need for a collaborative approach between vets, public health, livestock and animal welfare agencies.

The event takes place on Thursday, 19 September at Brangwyn Hall, Swansea. Tickets are free but must be reserved through the BVA website as places are limited.