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Chicken study sheds light on childhood eye disease
Scientists at the Roslin Institute studied chicken embryos to determine how fusion occurs.

New genes identified that are linked to ocular coloboma

A study of chicken embryos has identified new genes that could be responsible for the development of ocular coloboma in humans.

Ocular coloboma causes part of the eye to be missing at birth, severely affecting the patient’s vision. It accounts for up to 10 per cent of all childhood blindness and cannot be treated.

The disease is the result of errors in tissue fusion, which is essential for the formation of the eye and many other organs of the developing embryo.

Scientists at the Roslin Institute studied chicken embryos to determine how fusion occurs and identified genes that are switched on or off during the process.

One of the many newly identified genes included Netrin-1, which scientists say is likely to be critical in humans and other species, as well as in organs other than the eye.

Lead author Dr Joe Rainger said: “Identifying new genes and processes involved in tissue fusion will improve our understanding of how fusion defects occur, and whether these may be preventable.

"The fusion-genes we have revealed are also an excellent resource to support the identification of genetic defects in patient sequencing programmes.”

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AWF Student Grant open for submissions

News Story 1
 Applications are open for the Animal Welfare Foundation (AWF) Student Grant Scheme for innovative research projects designed to impact animal welfare.

Undergraduate and postgraduate students of veterinary science, veterinary nursing, agriculture studies and animal welfare are invited to submit their proposals to undertake research projects next year.

Grants are decided based on the project’s innovation, relevance to topical animal welfare issues and ability to contribute towards raising animal welfare standards. For more information visit animalwelfarefoundation.org.uk.  

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News Shorts
SPANA film highlights plight of working animals overseas

Animal welfare charity SPANA (The Society for the Protection of Animals Abroad) has teamed up with Brian Blessed and other famous voices to highlight the plight of working animals overseas.

In a new animated film, the celebrities raise awareness by showing the solidarity of the UK's own working animals on strike. A sniffer dog (Brian Blessed), police horse (Peter Egan) and sheepdog (Deborah Meaden) are shown ignoring their duties and protesting in solidarity with animals in developing countries.

SPANA chef executive Geoffrey Dennis said: "We are so grateful to Deborah, Peter and Brian for lending their voices to our new film, and for speaking up for millions of working animals overseas. SPANA believes that a life of work should not mean a life of suffering, and it is only thanks to people’s generosity and support that we can continue our vital work improving the lives of these animals."