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Breakthrough in hunt for R. equi vaccine
R. equi is a deadly disease that causes severe, insidiously progressive pneumonia.

Disease causes severe pneumonia and can affect other organs

US researchers have made a significant breakthrough in the pursuit of a vaccine against Rhodococcus equi.

A study published in PLOS One describes the trial of a vaccine, which scientists say has the potential to save thousands of foals every year. The research was carried out by researchers at Texas A&M University and Harvard Medical School.

Senior author Dr Noah Cohen said: “After many decades of efforts, our research, funded by the Morris Animal Foundation, has led to the first effective vaccine protecting folks against infection with R.equi, considered the most common and important form of pneumonia in foals older than a few weeks of age.”

R. equi is a deadly disease that causes severe, insidiously progressive pneumonia. With a 20 to 40 per cent fatality rate, the condition can also affect the bones, abdominal lymph nodes, joints, eyes and brain.

In the trial, Dr Cohen and his team set out to see if vaccinating mares at three and six weeks prior to the birth of their foals could protect their young against foal pneumonia.

They found that antibodies that ward off pneumonia were transferred to the foals via the mares’ colostrum, which was critical to establish as horses lack the ability to transfer antibodies through the placenta. Most importantly, those antibodies were able to protect almost all the foals born to vaccinated mares from contracting pneumonia.

The team then carried out a small, randomised, controlled study of nine foals with R.equi. Five foals were given serum with high levels of antibodies against R equi and four were not. All five foals receiving the hyperimmune serum were protected against R equi pneumonia, whereas the foals that received standard plasma all developed pneumonia.

Researchers say that while further safety testing is ongoing, the early results appear to support the safe and effective use of this novel foal vaccine.  Furthermore, the results suggest that immunising donor horses with the vaccine could be used to produce plasma, which foals could be transfused to prevent R. equi pneumonia.

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Vets to run marathon for World Animal Protection

News Story 1
 Two recently graduated veterinary surgeons will be running the London Marathon in April to raise money for the charity World Animal Protection.

Alex Bartlett and Maeve O'Neill plan to run the race together if they are given the same start times.

Dr O'Neill said: "You're always limited in what you can do to help animals, so it is nice to raise money for a charity that helps animals around the world."

Dr Bartlett added: "I have never run a marathon before and am excited to run my first one for such a good cause!"

Both Dr Bartlett and Dr O'Neill have fundraising pages online. 

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News Shorts
BSAVA releases new Guide to Procedures

The British Small Animal Veterinary Association (BSAVA) has published a new edition of its Guide to Procedures for Small Animal Practice.

It has added four new procedures; cystostomy tube placement, endotracheal intubation, point-of-care ultrasound and wet-to-dry dressings.

BSAVA says that it is an essential step-by-step guide to diagnostic and therapeutic procedures performed in practice. The textbook includes new images and illustrations, as well as high-definition videos for use prior to procedures.

Nick Bexfield and Julia Riggs, editors of the new edition, said: "We have built upon the success of the previous editions by responding to the feedback received from the BSAVA readership, and hope this new guide helps to further increase the confidence and accuracy with which these procedures are performed."

Print copies are available in the BSAVA store, with a digital version in the BSAVA library.