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Komodo dragon blood shows promising antimicrobial properties
Komodo dragons eat the decaying flesh of dead animals and live in bacteria-rich environments. 
Scientists create synthetic peptide that helps to heal wounds

A novel way to kill antibiotic-resistant bacteria, inspired by the germ-fighting abilities of Komodo dragons, has been created by scientists in the US.

According to research published in the journal NPJ Biofilms and Microbiomes, the method kills antibiotic resistant bacteria whilst spurring the body’s cells to heal cuts faster.

The work is the result of a $7.57 million government contract to discover new bacterial infection-defeating compounds in the blood of Komodo dragons and crocodiles.

These reptiles eat the decaying flesh of dead animals and live in bacteria-rich environments, suggesting they have strong natural immunity.

“Synthetic germ-fighting peptides are a new approach to potentially defeat bacteria that have grown resistant to conventional antibiotics,” said microbiologist Monique van Hoek from George Mason University, Virginia.

“The antimicrobial peptides we’re tapping into represents millions of years of evolution in protecting immune systems from dangerous infections.”

The research is initially designed to help soldiers heal faster and protect them from biological weapons. Eventually, it could also be available in bandages sold in drug stores to help heal more mundane cuts and scrapes.

In the study, scientists analysed hundreds of peptides in the blood of a single Komodo dragon and discovered one that showed a promising combination of antimicrobial and anti-biofilm properties.

The researchers rearranged the peptide’s amino acids to create a modified, synthetic version. Named “DRAGN-1” in honour of the Komodo dragon, the peptide is the first Komodo-inspired peptide the team created in the lab from this research.

“The synthesised peptide DRGN-1 is not a Komodo dragon’s natural peptide,” Van Hoek said. “it’s been already to be stronger in terms of both potency and stability.”

The peptide is able to attack the sticky biofilm that protects the bacteria and helps them grow in wounds. After breaking down the biofilm barrier, the synthetic peptide kills the bacteria whilst simultaneously stimulating the patient’s cells to heal the wound.

“The next steps for DRGN-1 are to develop it into wound-healing products for veterinary medicine before moving to products designed for humans,” the researchers said.

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Charity reveals it treated thousands of pets with dental issues last year

News Story 1
 Battersea Dogs & Cats Home has revealed that its veterinary team performs dental procedures on more than 170 animals every month. Last year the charity says it extracted hundreds of teeth from more than 800 animals and carried out thousands of routine scales and polishes.

To combat the problem, Battersea is urging pet owners to get regular dental checks at their vets, implement a daily oral care routine, feed a good dental chew and only give toys that are designed for dogs, including gentle rubber toys that are less wearing on the teeth. 

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Voting opens for RCVS council elections

Eligible veterinary surgeons can now vote in this year’s RCVS Council elections. Four out of the 10 candidates are already on council and are standing for re-election: David Catlow, Mandisa Greene, Neil Smith, Susan Paterson. The remaining six candidates are not currently on council: John C Davies, Karlien Heyman, John Innes, Thomas Lonsdale, Matthew Plumtree and Iain Richards.

Further information on the candidates can be found on the RCVS website: