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US researchers teach rats to drive
The research team fashioned a tiny car out of a clear plastic food container.

Finding may inform future mental health treatments 

Researchers at the University of Richmond, Virginia, have taught rats how to drive little plastic cars.


In the study, published in the journal Behavioural Brain Research, rats were trained to drive in rectangular arenas. The rats who passed their test were rewarded with small pieces of cereal.


Researchers say their finding reveals rats’ brains are more flexible than previously thought, and could further inform scientists about treatment for mental health conditions, such as depression and anxiety.

Kelly Lambert, a professor of behavioural neuroscience at the University of Richmond, said: “We already knew that rodents could recognize objects, press bars, and find their way around mazes, but we wondered if rats could learn the more complex task of operating a moving vehicle.

“They learned to navigate the car in unique ways and engaged in steering patterns they had never used to eventually arrive at the reward.”

In the study, researchers fashioned a tiny car out of a clear plastic food container. The ‘car’ also had an aluminium floor and three copper bars for a steering wheel.

Researchers found that rats that took part in the study were more relaxed than they were before training. They assessed this by measuring the levels of two stress hormones in their blood - corticosterone, a marker of stress, and dehydroepiandrosterone (DHEA), which counteracts stress.

The researchers noted the ratio of DHEA to corticosterone in the rats’ droppings increased throughout their training. Interestingly, the rats had even higher DHEA levels (healthy hormone change) than in a previous study, in which they were driven around as passengers in a remote-controlled car.


“We concluded that the rats that actually learned to drive had a greater sense of control over their environment that was accompanied by increased DHEA — something like a rodent version of what we refer to as self-efficacy or agency in humans," said Lambert.


The researchers also found that rats housed in enriched environments learned the driving task, but rats housed in standard laboratory cages experienced problems with the task (i.e. they failed their 'driving test'.

"That means the complex living environment led to more behavioural flexibility and neuroplasticity," Lambert said. “This reminds us that our brains are constantly changing in response to our environments — and that we’re accountable for maintaining our brains moment-to-moment."

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RCVS Knowledge appoints Veterinary Evidence editor-in-chief

News Story 1
 RCVS Knowledge has welcomed Professor Peter Cockcroft as editor-in-chief for Veterinary Evidence.

A world-renowned expert in evidence-based veterinary medicine, Prof Cockcroft will lead the strategic development and editorial quality of the open-access journal. He was previously in the role from 2017-2020.

Katie Mantell, CEO of RCVS Knowledge, said: "We are excited about the extensive knowledge of evidence-based veterinary medicine and clinical veterinary research that Peter brings, and we look forward to working with him over this next phase of the journal's development." 

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Defra to host bluetongue webinar for vets

The Department for Environment, Food and Rural Affairs (Defra) will be hosting a webinar for veterinary professional on bluetongue on Thursday, 25 April 2024.

Topics covered will include the transmission cycle, pathology and pathogenesis, clinical signs (including signs seen in recent BTV-3 cases in the Netherlands), and control and prevention.

The session, which will take place from 6pm to 7.30pm, is part of Defra's 'Plan, Prevent and Protect' webinar series, which are hosted by policy officials, epidemiologists and veterinary professionals from Defra and the Animal and Plant Health Agency. The bluetongue session will also feature insights from experts from The Pirbright Institute.

Those attending will have the opportunity to ask questions. Places on the webinar can be booked online.